2001年〜2005年

  • Kockelkorn TT, Arai M, Matsumoto H, Fukuda N, Yamada K, Minabe Y, Toyota T, Ujike H, Sora I, Mori N, Yoshikawa T, Itokawa M. Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia. Neurosci Lett. 368:41-45, 2004
  • 新井誠, 山田和男, 豊田倫子, 羽賀誠一, 氏家寛, 曽良一郎, 池田和彦, 吉川武男, 糸川昌成. 双極性障害および統合失調症における性差と神経細胞接着分子の関連研究. 脳と精神の医学. 15:477-488,2004
  • Itokawa M, Kasuga T, Yoshikawa T, Matsushita M. Identification of a male schizophrenic patient carrying a de novo balanced translocation, t(4; 13)(p16.1; q21.31). Psychiatry Clin Neurosci. 58:333-337,2004
  • Yamada K, Iwayama-Shigeno Y, Yoshida Y, Toyota T, Itokawa M, Hattori E, Shimizu H, Yoshikawa T. Family-based association study of schizophrenia with 444 markers and analysis of a new susceptibility locus mapped to 11q13.3. Am J Med Genet. 127B:11-19, 2004
  • Miyasaka T, Tatebayashi Y, Chui DH, Akagi T, Mishima Ki, Iwasaki K, Fujiwara M, Tanemura K, Murayama M, Ishiguro K, Planek E, Sato S, Hashikawa T, *Takashima A. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. In: Molecular neurobiology of Aizheimer disease and related disorders (Takeda M, Tanaka T, Cacabelos R, eds). Basel: Karger 215-224 2004
  • Grundke-Iqbal I, Tatebayashi Y, Lee MH, Li L, *Iqbal K. Neurogenesis: a promising therapeutic target for Alzheimer disease and related disorders. In: Molecular neurobiology of Aizheimer disease and related disorders (Takeda M, Tanaka T, Cacabelos R, eds). Basel: Karger 172-182 2004
  • Tatebayashi Y, Sato S, Akagi T, Chui DH, Miyasaka T, Planel E, Murayama M, *Takashima A. Deregulation of GSK-3beta and JNK in a mouse model of tauopathy: a kinase combination that induces Alzheimer-type tau hyperphorylation. In: Molecular neurobiology of Aizheimer disease and related disorders (Takeda M, Tanaka T, Cacabelos R, eds). Basel: Karger 62-70 2004
  • Tatebayashi Y, Haque N, Tung YC, Iqbal K, *Grundke-Iqbal I. Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport. J Cell Sci 117:1653-1663 2004
  • Planel E, Miyasaka T, Launey T, Chui DH, Tanemura K, Sato S, Murayama O, Ishiguro K, Tatebayashi Y, *Takashima A. Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease. J Neurosci 24:2401-2411 2004
  • Arai M, Itokawa M, Yamada K, Toyota T, Arai M, Haga S, Ujike H, Sora I, Ikeda K, Yoshikawa T. Association of neural cell adhesion molecule 1 gene polymorphisms with bipolar affective disorder in Japanese individuals. Biol Psychiatry. 55:804-810., 2004
  • Toyota T, Yoshitsugu K, Ebihara M, Yamada K, Ohba H, Fukasawa M, Minabe Y, Nakamura K, Sekine Y, Takei N, Suzuki K, Itokawa M, Meerabux JM, Iwayama-Shigeno Y, Tomaru Y, Shimizu H, Hattori E, Mori N, Yoshikawa T. Association between schizophrenia with ocular misalignment and polyalanine length variation in PMX2B. Hum Mol Genet. 13:551-561, 2004
  • Itokawa M, Arai M, Kato S, Ogata Y, Furukawa A, Haga S, Ujike H, Sora I, Ikeda K, Yoshikawa T. Association between a novel polymorphism in the promoter region of the neuropeptide Y gene and schizophrenia in humans. Neurosci Lett. 347:202-204, 2003
  • Kikuchi M, Yamada K, Toyota T, Itokawa M, Hattori E, Yoshitsugu K, Shimizu H, Yoshikawa T. Two-step association analyses of the chromosome 18p11.2 region in schizophrenia detect a locus encompassing C18orf1. Mol Psychiatry. 8:467-469, 2003
  • Itokawa M, Yamada K, Iwayama-Shigeno Y, Ishitsuka Y, Detera-Wadleigh S, Yoshikawa T. Genetic analysis of a functional GRIN2A promoter (GT)n repeat in bipolar disorder pedigrees in humans. Neurosci Lett. 345:53-56, 2003
  • Itokawa M, Yamada K, Yoshitsugu K, Toyota T, Suga T, Ohba H, Watanabe A, Hattori E, Shimizu H, Kumakura T, Ebihara M, Meerabux JM, Toru M, Yoshikawa T. A microsatellite repeat in the promoter of the N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene suppresses transcriptional activity and correlates with chronic outcome in schizophrenia. Pharmacogenetics. 13:271-278, 2003
  • Itokawa M, Lin Z, Uhl GR. Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations. Brain Res Mol Brain Res. 108:71-80, 2002
  • Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR. Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci U S A. 98(9):5300-5305. 2001