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論文
- タイトル
- タイトル（英）
- The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis.
- 参照URL
- https://researchmap.jp/read0160429/published_papers/37963989
- 著者
- 著者（英）
- Yoko Hasegawa,Thais Huarancca Reyes,Tomohiro Uemura,Anirban Baral,Akari Fujimaki,Yongming Luo,Yoshie Morita,Yasushi Saeki,Shugo Maekawa,Shigetaka Yasuda,Koki Mukuta,Yoichiro Fukao,Keiji Tanaka,Akihiko Nakano,Junpei Takagi,Rishikesh P Bhalerao,Junji Yamaguchi,Takeo Sato
- 担当区分
- 概要
- 概要（英）
- Ubiquitination is a post-translational modification involving the reversible attachment of the small protein ubiquitin to a target protein. Ubiquitination is involved in numerous cellular processes, including the membrane trafficking of cargo proteins. However, the ubiquitination of the trafficking machinery components and their involvement in environmental responses are not well understood. Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions. SYP61 is a key component of membrane trafficking in Arabidopsis. The subcellular localization of ATL31 was disrupted in knockdown mutants of SYP61, and the insensitivity of ATL31-overexpressing plants to high C/low N-stress was repressed in these mutants, suggesting that SYP61 and ATL31 cooperatively function in plant responses to nutrient stress. SYP61 is ubiquitinated in plants, and its ubiquitination level is upregulated under low C/high N-nutrient conditions. These findings provide important insights into the ubiquitin signaling and membrane trafficking machinery in plants.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- The Plant cell
- 巻
- 34
- 号
- 4
- 開始ページ
- 1354
- 終了ページ
- 1374
- 出版年月
- 2022年3月29日
- 査読の有無
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.1093/plcell/koac014
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