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論文
- タイトル
- タイトル（英）
- The ventral striatum contributes to the activity of the motor cortex and motor outputs in monkeys
- 参照URL
- https://researchmap.jp/michiaki_suzuki/published_papers/39982990
- 著者
- 著者（英）
- Michiaki Suzuki,Yukio Nishimura
- 担当区分
- 概要
- 概要（英）
- <jats:p>The ventral striatum (VSt) is thought to be involved in the vigor of motivated behavior and is suggested to be a limbic-motor interface between limbic areas involved in motivational processes and neural circuits regulating behavioral outputs. However, there is little direct evidence demonstrating the involvement of the VSt in motor control for motivated behaviors. To clarify the functional role of the VSt in motor control, we investigated the effect of reversible pharmacological inactivation of the VSt on the oscillatory activity of the sensorimotor cortices and motor outputs in two macaque monkeys. VSt inactivation reduced movement-related activities of the primary motor cortex and premotor area at 15–120 Hz and increased those at 5–7 Hz. These changes were accompanied by reduced torque outputs but had no effect on the correct performance rate. The present study provides direct evidence that the VSt regulates activities of the motor cortices and motor output.</jats:p>
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Frontiers in Systems Neuroscience
- 巻
- 号
- 開始ページ
- 終了ページ
- 出版年月
- 2022年8月29日
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 1662-5137
- DOI URL
- https://doi.org/10.3389/fnsys.2022.979272
- 共同研究・競争的資金等の研究課題