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論文
- タイトル
- タイトル（英）
- Morphological study of the phrenic nerve to determine a reference value for the myelinated fiber density in elderly individuals
- 参照URL
- https://researchmap.jp/Ito_K/published_papers/40720494
- 著者
- 著者（英）
- Atsuko Motoda,Tomoyasu Matsubara,Zen-ichi Tanei,Yasuhiro Sakashita,Mikihiro Yamazaki,Ito Kawakami,Renpei Sengoku,Tomio Arai,Hirofumi Maruyama,Yuko Saito,Shigeo Murayama
- 担当区分
- 概要
- 概要（英）
- Phrenic nerves (PNs) play an important role in respiration; however, very few morphological studies have assessed them. This study aimed to provide control reference values, including the density of large and small myelinated PN fibers, for future pathological studies. We assessed a total of nine nerves from eight cases among consecutive autopsy cases registered to the Brain Bank for Aging Research between 2018 and 2019 (five men and three women, mean age 77.0 +/- 7.0 years). The nerves were sampled distally, and their structures were analyzed using semi-thin sections stained with toluidine blue. The mean and standard deviation of the density of each myelinated fiber of the PN was 6908 +/- 1132 fibers/mm(2) (total myelinated fiber), 4095 +/- 586 fibers/mm(2) (large diameter myelinated fiber; diameter >= 7 mu m), and 2813 +/- 629 fibers/mm(2) (small diameter myelinated fiber; diameter <7 mu m). There was no correlation between myelinated fiber density and age. This study provides the density measurement of the human PN myelinated fiber, and these findings can be used as reference values for the PN in elderly individuals.
- 出版者・発行元
- 出版者・発行元（英）
- WILEY
- 誌名
- 誌名（英）
- NEUROPATHOLOGY
- 巻
- 号
- 開始ページ
- 終了ページ
- 出版年月
- 2022年8月
- 査読の有無
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 0919-6544
- DOI URL
- https://doi.org/10.1111/neup.12856
- 共同研究・競争的資金等の研究課題
研究者
河上 緒
(カワカミ イト)