※ をクリックすると外部の論文のサイトが開きます。
論文
- タイトル
- タイトル（英）
- Update of the FANTOM web resource: enhancement for studying noncoding genomes.
- 参照URL
- https://researchmap.jp/satide/published_papers/48916845
- 著者
- 著者（英）
- Tomoe Nobusada,Chi Wai Yip,Saumya Agrawal,Jessica Severin,Imad Abugessaisa,Akira Hasegawa,Chung Chau Hon,Satoru Ide,Masaru Koido,Atsushi Kondo,Hiroshi Masuya,Shinya Oki,Michihira Tagami,Toyoyuki Takada,Chikashi Terao,Nishad Thalhath,Scott Walker,Kayoko Yasuzawa,Jay W Shin,Michiel J L de Hoon,Piero Carninci,Hideya Kawaji,Takeya Kasukawa
- 担当区分
- 概要
- 概要（英）
- The FANTOM web resource (https://fantom.gsc.riken.jp/) has been a unique resource for studying mammalian genomes, which is built on the research activities conducted in the international collaborative project FANTOM (Functional ANnoTation Of the Mammalian genome). In recent updates, we expanded annotations for long non-coding RNAs (lncRNAs) and transcribed cis-regulatory elements (CREs). The former was derived from the large-scale lncRNA perturbations in induced pluripotent stem cells (iPSCs) and integrative analysis of Hi-C data conducted in the sixth iteration of the project (FANTOM6). The resulting annotations of lncRNAs, according to the impact on cellular and molecular phenotypes and the potential RNA-chromatin interactions, are accessible via the interactive ZENBU-Reports framework. The latter involves a new platform, fanta.bio (https://fanta.bio/), which collects transcribed CREs identified via use of an extended dataset of CAGE profiles. The CREs, with their annotations including genetic and epigenetic information, are accessible via a dedicated interface as well as the UCSC Genome Browser Database. These updates offer enhanced opportunities to investigate the functions of non-coding regions within mammalian genomes.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Nucleic acids research
- 巻
- 53
- 号
- D1
- 開始ページ
- D419-D424
- 終了ページ
- 出版年月
- 2025年1月6日
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.1093/nar/gkae1047
- 共同研究・競争的資金等の研究課題