
		
{"id":2799,"date":"2022-10-08T16:26:29","date_gmt":"2022-10-08T07:26:29","guid":{"rendered":"https:\/\/www.igakuken.or.jp\/genome?page_id=2799"},"modified":"2022-10-10T12:10:18","modified_gmt":"2022-10-10T03:10:18","slug":"greetingsmembers","status":"publish","type":"page","link":"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799","title":{"rendered":"Greetings + Members"},"content":{"rendered":"<div id=\"toc-np-container\"><p id=\"toc-np-title\">Contents<\/p><ul class=\"no-bullets\"><li class=\"header-level-1\"><a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799#1-OVERVIEW\">1 OVERVIEW<\/a><\/li><li class=\"header-level-1\"><a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799#2-Short-personal-history-of-the-leader\">2 Short personal history of the leader<\/a><\/li><li class=\"header-level-1\"><a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799#3-Current-research-subjects\">3 Current research subjects<\/a><\/li><li class=\"header-level-1\"><a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799#4-Current-members-of-the-lab-October-2022Crick\">4 Current members of the lab (October, 2022)[Crick!]<\/a><\/li><li class=\"header-level-1\"><a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799#5Recent-events-under-construction-in-English-please-see-the-Japanese-HP\">5\u00a0Recent events (under construction in English; please see the Japanese HP)<\/a><\/li><\/ul><\/div><h2><span id=\"1-OVERVIEW\">1 OVERVIEW<\/span><\/h2>\n<p>Our goal is to understand the molecular mechanisms underlying the faithful inheritance of genetic materials and stable maintenance of the genome. Toward this goal, we are studying various aspects of chromosome dynamics, with particular focus on regulation during S phase, using &lt;i&gt;E. coli&lt;\/i&gt;, fission yeast, and mammalian cells. We try to elucidate how chromosomes replicate and how the inheritance of the replicated chromosomes is regulated to enable stable maintenance of the genome through generations. Answers to these questions will shed light on how defects in these processes may contribute to the development of diseases, including cancers, and to senescence. It will also help to identify novel target proteins for cancer therapies. There are three major issues associated with genome DNA replication.<\/p>\n<p>&nbsp;<\/p>\n<p>\u2460 Once and only once replication of a genome during a cell cycle and its strict coordination with mitosis.<\/p>\n<p>\u2461 DNA replication during S phase is under sptiao-temporal regulation and the process is intimately related to epigenome maintenance and alterations.<\/p>\n<p>\u2462 DNA replication encounters various threats along the course of the process. Cells need to cope with these \u201creplication stress\u201d to ensure completion of the entire genome duplication without major errors.<\/p>\n<p>&nbsp;<\/p>\n<p>The failures in \u2460 and \u2462 are directly linked to increased genome instability and generation of cell populations of abnormal growth. In order to elucidate mechanisms associated with these issues, we are working on the following four major subjects.<\/p>\n<p>&nbsp;<\/p>\n<p>1) How are the timing and nuclear localization of DNA replication determined, and how is it related to the processes of other chromosome transactions. We discovered crucial roles of Rif1, an evolutionally conserved nuclear factor, in genome-wide regulation of replication timing (<strong>Figure 1<\/strong>). We are particularly interested in how association of Rif1 with nuclear membrane contributes to regulation of not only replication timing but also other events such as DSB repair and transcription.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-3341 size-large\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-620x477.jpg\" alt=\"\" width=\"620\" height=\"477\" srcset=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-620x477.jpg 620w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-300x231.jpg 300w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-768x590.jpg 768w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-1536x1181.jpg 1536w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_1English-2048x1575.jpg 2048w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/><\/p>\n<p><strong>Figure 1\u00a0<span lang=\"EN-US\">Regulation of chromatin architecture for establishing replication timing domains. <\/span><\/strong><\/p>\n<p><span lang=\"EN-US\">Rif1 facilitates chromatin loop formation through its binding to G4 structures present in the intergenic segments and its multimerization activitiy. This will generate chromatin architecture that may be related to the replication timing domain structures.<\/span><\/p>\n<p>2) Biological functions of G-quadruplex, especially in regulation of DNA replication. \u00a0\u00a0\u00a0\u00a0\u00a0Based on our findings, we have come to realize the crucial and ubiquitous roles of non-B DNA, more specifically, G-quadruple structures. Recent numerous reports indicate the essential roles of various G4 structures in transcription, recombination, genome rearrangement, epigenome regulation and others (<strong>Figure 2<\/strong>). Through analyzing the roles of G4 structures in replication initiation and chromatin regulation, we would like to disclose more general biological functions of G4 structures.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-3339 size-large\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English-620x327.jpg\" alt=\"\" width=\"620\" height=\"327\" srcset=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English-620x327.jpg 620w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English-300x158.jpg 300w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English-768x405.jpg 768w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English-1536x809.jpg 1536w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_2English.jpg 1602w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/><\/p>\n<p><strong>Figure 2\u00a0<span lang=\"EN-US\">Potential biological roles of G4.<\/span><\/strong><\/p>\n<p><span lang=\"EN-US\">Increasing numbers of reports indicate the crucial roles of G4, formed on DNA, RNA and RNA-DNA hybrids, in various chromosome transactions.<\/span><\/p>\n<div><\/div>\n<p>3) Mechanisms of cellular responses to replication stress and how are they connected other diverse cellular stress responses. DNA replication needs to continue until the entire genome is replicated, once it is initiated. The block to ongoing DNA replication is a threat to the genomic integrity, and needs to be removed swiftly. Claspin\/Mrc1 is a key protein that transmits the replication stress signal to the downstream effectors. We have discovered a novel function of Mrc1\/Claspin in regulation of initiation through interaction with Cdc7 kinase. We also discovered a crucial role of Cdc7 in activating replication checkpoint through phosphorylation of Claspin (<strong>Figure 3<\/strong>). Furthermore, we have shown that Claspin is required also for cells to resume growth after serum starvation and for their responses to other forms of stresses including osmotic shock and high temperature (<strong>Figure 4<\/strong>).<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-3337 size-large\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-620x426.jpg\" alt=\"\" width=\"620\" height=\"426\" srcset=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-620x426.jpg 620w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-300x206.jpg 300w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-768x528.jpg 768w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-1536x1056.jpg 1536w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_3English-2048x1407.jpg 2048w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/><\/p>\n<p><strong>Figure 3\u00a0<span lang=\"EN-US\">Differential mechanism of replication stress responses in cancer and non-cancer cells.<\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span lang=\"EN-US\">A conserved pathway induced by replication stress is drawn to the right corner of the figure. In this pathway, Claspin needs to be phosphorylated at a conserved CKBD motif to facilitate the binding of Chk1 kinase to Claspin. In cancer cells, Cdc7 is mainly responsible for this phosphorylation, whereas in non-cancer cells, CK1 (casein kinase 1<\/span><span lang=\"EN-US\">g<\/span><span lang=\"EN-US\">1) plays a predominant role. This differential mechanism can be exploited to develop a strategy for cancer cell-specific cell killing by targeting Cdc7 kinase.<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-3335 size-large\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_4-English-620x472.jpg\" alt=\"\" width=\"620\" height=\"472\" srcset=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_4-English-620x472.jpg 620w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_4-English-300x228.jpg 300w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_4-English-768x585.jpg 768w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_4-English.jpg 793w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/><\/p>\n<p><strong>Figure 4\u00a0Formation of cancer cells.<\/strong><\/p>\n<p>Various cellular stresses could induce replication stress, thus activating Claspin-dependent checkpoint pathway. DNA damages are transiently induced by replication stress, but eventually removed by cellular DNA repair system. Once this cellular defense system is compromised, genome integrity is lost and cells are transformed into cancer state.<\/p>\n<p>4) Roles of replication factors in development of individual organs and tissues and potential mechanistic diversification of replication systems. We are interested in the in vivo roles of cell cycle\/ checkpoint factors, and are making mutant mice in which these genes are conditionally knocked out in specific tissues\/ organs by using the Cre-loxP system (<strong>Figure 5<\/strong>). We are also developing novel anti-cancer strategies utilizing cell cycle regulators as a target.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-3333 size-large\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-620x493.jpg\" alt=\"\" width=\"620\" height=\"493\" srcset=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-620x493.jpg 620w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-300x239.jpg 300w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-768x611.jpg 768w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-1536x1222.jpg 1536w, https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2022\/10\/hisaomasai_5English-2048x1630.jpg 2048w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Figure 5\u00a0<span lang=\"EN-US\">Cdc7 knockout in neural stem cells causes defect in brain formation and growth retardation after birth.<\/span><\/strong><\/p>\n<div><span lang=\"EN-US\">Cdc7 (f\/+) <i>Nestin<sup>Cre\u00a0<\/sup><\/i><\/span><span style=\"font-size: 14.079999923706055px;\">mice are born, but exhibit abnormal walking and limb-clasping reflexes, growth retardation and die by 20 days after birth.<\/span><\/div>\n<div><\/div>\n<h2><span id=\"2-Short-personal-history-of-the-leader\">2 Short personal history of the leader<\/span><\/h2>\n<p><em><strong>EDUCATION &amp; DEGREE<\/strong><\/em><\/p>\n<p>1981\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 B.S., Dept. Biochemistry and Biophysics, Faculty of Science, University of Tokyo,<\/p>\n<p>1986\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ph.D., University of Tokyo<\/p>\n<p>&nbsp;<\/p>\n<p><em><strong>EMPLOYMENT<\/strong><\/em><\/p>\n<p>1990 \u00a0\u00a0\u00a0\u00a0\u00a0 Assist. Prof., Dept. Mol. Dev. Biol., Inst. Med. Sci., Univ. Tokyo<\/p>\n<p>1995 \u00a0\u00a0\u00a0\u00a0\u00a0 Assoc. Prof., Dept. Mol. Dev. Biol., Inst. Med. Sci., Univ. Tokyo<br \/>\n2000 \u00a0\u00a0\u00a0\u00a0\u00a0 Laboratory Head, Dept. Cell Biol., Tokyo Metropol. Inst. Med. Sci.<\/p>\n<p>2004~\u00a0\u00a0\u00a0\u00a0\u00a0 Visiting Professor, The University of Tokyo, Graduate School of Frontier Sciences<\/p>\n<p>2011\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Department Director, Dept. Genome Medicine, Tokyo Metropol. Inst. Med. Sci.<\/p>\n<p>2012\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Director of the Center for the Basic Technology Research Center, Tokyo Metropol. Inst. Med. Sci.<\/p>\n<p>2015~\u00a0\u00a0\u00a0\u00a0\u00a0 Vice Director General, Tokyo Metropol. Inst. Med. Sci.<\/p>\n<p>2018~ \u00a0Director General, Tokyo Metropol. Inst. Med. Sci.<\/p>\n<p>&nbsp;<\/p>\n<p><em><strong>EDITORIAL SERVICES<\/strong><\/em><\/p>\n<p>Editorial Board Member,<em> Journal of Biological Chemistry<\/em> (2009~2014)<\/p>\n<p>Associate Editor, <em>Genes to Cells<\/em> (2009~)<\/p>\n<p>Associate Editor, <em>Journal of Biochemistry<\/em> (2010~2012; 2017~)<\/p>\n<p>Faculty1000 (Faculty Opinions) member (2011~)<\/p>\n<p>Editor, <em>Biochemical and Biophysical Research Communications<\/em> (2014~)<\/p>\n<p>&nbsp;<\/p>\n<p><em><strong>AWARDS<\/strong><\/em><\/p>\n<p>2006: Tokyo Metropolitan Award<\/p>\n<p>2012: A-IMBN (Asian International Molecular Biology Network) Arthur Kornberg Memorial Award<\/p>\n<p>2017: 2017\u00a0Prize for Science and Technology (Research Category),\u00a0the Commendation for Science and Technology by the Minister of Education,\u00a0Culture, Sports, Science and Technology.<\/p>\n<p>&nbsp;<\/p>\n<p><em><strong>RECENT PUBLICATIONS (Excerpt)<\/strong><\/em><\/p>\n<ol>\n<li>Masai, H. <em>et al.<strong> Annual Rev. Biochem.<\/strong><\/em> 79, 89-130. (2010)<\/li>\n<li>Matsumoto, S. <em>et al.<\/em>\u00a0<strong><em>J.\u00a0Cell Biol.<\/em><\/strong> 195, 387-401. (2011)<\/li>\n<li>Hayano, M. <em>et al. <strong>Genes and Development<\/strong><\/em> 26,137-150. (2012)<\/li>\n<li>Yamazaki, S. <em>et al.<\/em> <strong><em>EMBO J.<\/em><\/strong> 31, 3667-3677. (2012)<\/li>\n<li>Yamada, M. <em>et al.<\/em> <strong><em>Genes and Development<\/em><\/strong> 27:2459-2472. (2013)<\/li>\n<li>Kanoh <em>et al.<\/em>\u00a0<strong><em>Nat.\u00a0Struct. Mol. Biol.<\/em><\/strong> 22:889-897. (2015)<\/li>\n<li>Yang <em>et al.<\/em> <strong><em>Nat.\u00a0<\/em><\/strong><strong><em> Commun.<\/em><\/strong> 7:12135. (2016)<\/li>\n<li>Matsumoto <em>et al.<\/em> <strong><em>J.\u00a0<\/em><\/strong><strong><em>Cell. Biol.<\/em><\/strong> pii: e00355-16. (2017)<\/li>\n<li>Yang <em>et al.<\/em> <strong><em>E-life<\/em><\/strong> pii: e50796. (2019)<\/li>\n<li>Irie, T. <em>et al.<\/em>\u00a0<strong><em>J.\u00a0Med. Chem<\/em><\/strong>. 64(19):14153-14164. (2021)<\/li>\n<li>Yoshizawa-Sugata, Y. <em>et al.<\/em><strong><em>\u00a0J.\u00a0Biol. Chem.<\/em><\/strong>, 297(6):101367. (2021)<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h2><span id=\"3-Current-research-subjects\">3 Current research subjects<\/span><\/h2>\n<p>(1) Universality and Diversity of DNA replication systems and their evolution<\/p>\n<p>(2) Regulation of Spatio-temporal regulation of replication program through chromatin architecture and its spatial arrangement<\/p>\n<p>(3) Dynamic formation and resolution of cellular G-quadruplex structures and their biological functions<\/p>\n<p>(4) Cellular responses to replication stress and maintenance of genomic integrity: crosstalks with biological stress responses and relevance to cancer development<\/p>\n<p>(5) Novel strategies for anti-cancer treatment targeting replication factors<\/p>\n<p>(6) Roles of replication factors in development and functions of various organs and tissues<\/p>\n<h2><span id=\"4-Current-members-of-the-lab-October-2022Crick\">4 Current members of the lab (October, 2022)[Crick!]<\/span><\/h2>\n<p><strong style=\"font-size: 14px;\">Project Leader: Hisao Masai<\/strong><\/p>\n<p><a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/03\/H_Masai.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-thumbnail wp-image-68\" src=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/03\/H_Masai-150x150.jpg\" alt=\"H_Masai\" width=\"150\" height=\"150\" \/><\/a><\/p>\n<table border=\"0\" width=\"469\" cellspacing=\"0\" cellpadding=\"0\">\n<colgroup>\n<col width=\"130\" \/>\n<col width=\"118\" \/>\n<col width=\"114\" \/>\n<col width=\"107\" \/><\/colgroup>\n<tbody>\n<tr>\n<td class=\"xl65\" colspan=\"4\" width=\"469\" height=\"19\">Current Laboratory Members<\/td>\n<\/tr>\n<tr>\n<td class=\"xl65\" height=\"19\"><strong>Sub leader<\/strong><\/td>\n<td class=\"xl65\" style=\"text-align: center;\" colspan=\"3\"><strong>Hiroyuki Sasanuma<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" rowspan=\"3\" height=\"57\">Staff Researchers<\/td>\n<td class=\"xl66\">You Zhiying<\/td>\n<td class=\"xl66\">Taku Tanaka<\/td>\n<td class=\"xl66\">Yutaka Kanoh<\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\">Tomohiro Iguchi<\/td>\n<td class=\"xl66\">Yoichi Tajima<\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\"><\/td>\n<td class=\"xl66\"><\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl72\" rowspan=\"2\" width=\"130\" height=\"39\">Researchers<\/td>\n<td class=\"xl66\">Sayuri Ito<\/td>\n<td class=\"xl66\">Chi-Chun Yang<\/td>\n<td class=\"xl66\">Kenji Moriyama<\/td>\n<\/tr>\n<tr>\n<td class=\"xl64\" height=\"21\"><\/td>\n<td class=\"xl64\"><\/td>\n<td class=\"xl64\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" rowspan=\"7\" height=\"303\">Students<\/td>\n<td class=\"xl67\" width=\"118\">Karin Hori<br \/>\n(PhD 4th year)<\/td>\n<td class=\"xl67\" width=\"114\">Tomoko Sagi<br \/>\n(PhD 4th year)<\/td>\n<td class=\"xl67\" width=\"107\">Shunsuke Kobayashi<br \/>\n(PhD 2nd year; leave of absence)<\/td>\n<\/tr>\n<tr>\n<td class=\"xl67\" width=\"118\" height=\"57\">Hao-Wen Hsiao<br \/>\n(PhD 1st year)<\/td>\n<td class=\"xl67\" width=\"114\">NGO THI TO TRINH<br \/>\n(PhD 1st year)<\/td>\n<td class=\"xl68\" width=\"107\">Yi Ding<br \/>\n(PhD 1st year)<\/td>\n<\/tr>\n<tr>\n<td class=\"xl68\" width=\"118\" height=\"57\">Manaho Sashida<br \/>\n(Master 1st year)<\/td>\n<td class=\"xl68\" width=\"114\">ZHEN WANXIN(Suzie)<br \/>\n(Master 1st year)<\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl67\" width=\"118\" height=\"38\">Kosuke Yamazaki<br \/>\n(BS 4th year)<\/td>\n<td class=\"xl67\" width=\"114\">Kanna Hotta<br \/>\n(BS 4th year)<\/td>\n<td class=\"xl67\" width=\"107\">Ayaka Onuki<br \/>\n(BS 4th year)<\/td>\n<\/tr>\n<tr>\n<td class=\"xl67\" width=\"118\" height=\"38\">Itsuki Fukumoto<br \/>\n(BS 3rd year)<\/td>\n<td class=\"xl67\" width=\"114\">Keisuke Katsuda<br \/>\n(BS 3rd year)<\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl68\" width=\"118\" height=\"57\">BAYRAK MELIH<br \/>\n(Intership Student)<\/td>\n<td class=\"xl68\" width=\"114\">WENXIN ZHENG<br \/>\n(Intership Student)<\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl65\" height=\"19\"><\/td>\n<td class=\"xl65\"><\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\">Research Associates<\/td>\n<td class=\"xl71\">Noaoko Kakusho<\/td>\n<td class=\"xl66\">Rino Fukatsu<\/td>\n<td class=\"xl66\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl70\" height=\"19\">Secretary<\/td>\n<td class=\"xl66\">Akiko Minagawa<\/td>\n<td class=\"xl66\"><\/td>\n<td class=\"xl66\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\">Laboratory assistances<\/td>\n<td class=\"xl66\">Kazuto Takayasu<\/td>\n<td class=\"xl66\">Yu Shiraki<\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\">Visiting Scientists<\/td>\n<td class=\"xl66\">So Maezawa<\/td>\n<td class=\"xl66\">Makiko Hirano<\/td>\n<td class=\"xl66\">Masayuki Yamada<\/td>\n<\/tr>\n<tr>\n<td class=\"xl66\" height=\"19\"><\/td>\n<td class=\"xl66\">Motoshi Hayano<\/td>\n<td class=\"xl66\"><\/td>\n<td class=\"xl66\"><\/td>\n<\/tr>\n<tr>\n<td class=\"xl67\" width=\"130\" height=\"38\">Senior Visiting Scientists<\/td>\n<td class=\"xl66\">Shoichiro Miyatake<\/td>\n<td class=\"xl66\">Hiroyuki Kato<\/td>\n<td class=\"xl66\">Takehiko Shibata<\/td>\n<\/tr>\n<tr>\n<td class=\"xl67\" width=\"130\" height=\"57\">Foreign Visiting Scientist<\/td>\n<td class=\"xl68\" width=\"118\">\u00a0Sebastian Jespersen Charlton<br \/>\n(Denmark)<\/td>\n<td class=\"xl65\"><\/td>\n<td class=\"xl65\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span id=\"5Recent-events-under-construction-in-English-please-see-the-Japanese-HP\">5\u00a0Recent events (under construction in English; please see the Japanese HP)<\/span><\/h2>\n<h4><strong>\u00a0\u00a0<\/strong><strong>2015\u5e74<\/strong><\/h4>\n<p>&nbsp;<\/p>\n<p>2015\u5e741\u670816\u65e5<\/p>\n<p>\u6d25\u7530\u30db\u30fc\u30eb\u306b\u3066\u5e73\u621026\u5e74\u5ea6\u3000\u7b2c\uff17\u56de\u3000\u90fd\u533b\u5b66\u7814\u3000\u90fd\u6c11\u8b1b\u5ea7\u300c\u30b2\u30ce\u30e0\u306e\u5897\u3048\u308b\u3057\u304f\u307f\u3068\u305d\u306e\u8d77\u6e90\u30fb\u9032\u5316\uff1a\u751f\u547d\u306e\u8d77\u6e90\u304b\u3089\u5730\u7403\u5916\u53ef\u80fd\u6027\u307e\u3067 \u300d\u304c\u958b\u50ac\u3002\u6b63\u4e95\u3068\u6771\u4eac\u85ac\u5927\u306e\u5c71\u5cb8\u660e\u5f66\u6559\u6388\u304c\u8b1b\u6f14\u3002<\/p>\n<div>2015\u5e742\u67088\u65e5<br \/>\n\u6a2a\u6d5c\u60c5\u5831\u6587\u5316\u30bb\u30f3\u30bf\u30fc \u60c5\u6587\u30db\u30fc\u30eb \u306b\u3066\u3001\u6587\u90e8\u79d1\u5b66\u7701\u65b0\u5b66\u8853\u7814\u7a76\u9818\u57df\u300c\u30b2\u30ce\u30e0\u3092\u652f\u3048\u308b\u975e\u30b3\u30fc\u30c9DNA \u9818\u57df\u306e\u6a5f\u80fd\u300d \u4e3b\u50ac \u9ad8\u6821\u751f\u5411\u3051\u516c\u958b\u8b1b\u5ea7\u300c\u30b2\u30ce\u30e0\u306e\u8abf\u3079\u300d\u304c\u958b\u50ac\u3055\u308c\u308b\u30022015\u5e742\u670812\u65e5<br \/>\n\u9280\u5ea7\u30df\u30ec\u30b8\u30e0\u306b\u3066\u65e7\u53cb\u3068\u518d\u4f1a\u3002<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/04\/caeabcb5755e858638895985acde293f.pdf\">\u5199\u771f\u3002<\/a>2015\u5e742\u670822\u65e5<br \/>\n\u6771\u4eac\u30de\u30e9\u30bd\u30f3\u958b\u50ac\u3002\u5f53\u7814\u7a76\u5ba4\u306e\u65b0\u672c\u7f8e\u667a\u679d\u3055\u3093\u304c\u53c2\u52a0\u3002\uff13\u6642\u9593\uff11\uff10\u5206\u3067\u5b8c\u8d70\u3002\u5c71\u5d0e\u541b\u3068\u5fdc\u63f4\u306b\u3044\u304d\u307e\u3057\u305f\u3002<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/03\/P1030823.jpg\">\u5199\u771f\u306f\u3053\u3061\u30891\u3002<\/a>\u00a0<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/03\/P1030827-e1426737285207.jpg\">2<\/a> <a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/03\/P1030829-e1426737267996.jpg\">3<\/a><br \/>\n\uff08\u829d\u5d0e\u592a\u5148\u751f\u3082\u521d\u30de\u30e9\u30bd\u30f3\u3000\u597d\u8a18\u9332\u304a\u3081\u3067\u3068\u3046\u3054\u3056\u3044\u307e\u3059\uff01\uff092015\u5e742\u670825-26\u65e5<br \/>\n\u7b2c\u4e00\u56de\u533b\u5b66\u7814\u30ea\u30c8\u30ea\u30fc\u30c8\u3000\u304b\u305a\u3055\u30a2\u30ab\u30c7\u30df\u30a2\u30db\u30fc\u30eb\u3067\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\u30022015\u5e743\u670826\u65e5\u8b1b\u6f14<br \/>\n\u533b\u7642\u306e\u30d1\u30e9\u30c0\u30a4\u30e0\u30b7\u30d5\u30c8\uff5e \u60c5\u5831\u9769\u547d\u3068\u30d0\u30a4\u30aa\u30e1\u30c7\u30a3\u30ab\u30eb\u9769\u547d\u306e\u30b7\u30b9\u30c6\u30e0\u878d\u5408 \uff5e\u3000(\u304b\u306a\u304c\u308f\u30b5\u30a4\u30a8\u30f3\u30b9\u30d1\u30fc\u30af 3 \u968eKSP \u30db\u30fc\u30eb)2015\u5e744\u670810\u65e5 Genes to Cells \u7de8\u96c6\u59d4\u54e1\u4f1a<\/div>\n<p>2015\u5e744\u670827\u65e5\u3000\u53ca\u3073\u30005\u670811\u65e5\u3000\u6771\u4eac\u7406\u79d1\u5927\u5b66\u3000\u751f\u7269\u79d1\u5b66\u7279\u5225\u8b1b\u7fa9III\uff08\u904b\u6cb3\uff09<\/p>\n<p>2015\u5e745\u670814\u65e5\u3000\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u3000\u65b0\u9818\u57df\u5275\u6210\u79d1\u5b66\u7814\u7a76\u79d1\u3000\u30e1\u30c7\u30a3\u30ab\u30eb\u60c5\u5831\u751f\u547d\u5c02\u653b<br \/>\n\u767a\u5c55\u8b1b\u7fa9\u2163\uff08\u7d30\u80de\u9ad8\u6b21\u6a5f\u80fd\u306e\u6700\u5148\u7aef\uff09<br \/>\n\u300cDNA\u8907\u88fd\u5236\u5fa1\u306e\u591a\u69d8\u6027\u3001\u53ef\u5851\u6027\u3068\u9032\u5316\u305d\u3057\u3066\u75be\u60a3\u3068\u306e\u95a2\u9023\u300d<\/p>\n<p>2015\u5e745\u670818~19\u65e5\u3000BBRC Bangalore meeting (Bangalore, India)<br \/>\nMay 18th (Monday) BBRC symposium at the National Centre for Biological Science (Title of the lecture: Biological roles of G-quadruplex structures )<br \/>\nMay 19th (Tuesday) BBRC Board Meeting at The Taj West End<\/p>\n<p>2015\u5e745\u670813\u65e5\u30016\u67083,10\u65e5\u3000\u6771\u4eac\u5927\u5b66\u3000\u7406\u5b66\u90e8\u3000\u751f\u7269\u5316\u5b66\u79d1\u300c\u7d30\u80de\u5206\u5b50\u751f\u7269\u5b66\uff11\u300d\u8b1b\u7fa9\u3000(\u51683\u56de)<\/p>\n<p>2015\u5e746\u67084~5\u65e5\u3000\u5927\u8178\u83cc\u7814\u7a76\u4f1a\uff08\u7435\u7436\u6e56\u30b0\u30e9\u30f3\u30c9\u30db\u30c6\u30eb\u30fb\u4eac\u8fd1\u6c5f\uff09<\/p>\n<p>2015\u5e746\u670821~26\u65e5\u3000 8th international fission yeast meeting in Kobe\u3000\u60c5\u5831\u306f\u3053\u3061\u3089\u3002<\/p>\n<p>2015\u5e746\u670829~30\u65e5\u3000\u97d3\u56fd3\u5927\u5b66\u30fc\u533b\u5b66\u7814\u56fd\u969b\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff08\u6771\u4eac\u90fd\u533b\u5b66\u7814\uff09<\/p>\n<p>2015\u5e747\u67081~2\u65e5\u3000CBSM2015 \u30b0\u30e9\u30f3\u30c8\u30a8\u30af\u30b7\u30d6\u90a3\u9808\u767d\u6cb3<\/p>\n<p>2015\u5e748\u67085~8\u65e5\u3000\u65b0\u5b66\u8853\u9818\u57df\u300c\u975e\u30b3\u30fc\u30c9DNA\u300d\u7b2c\uff19\u56de\u9818\u57df\u4f1a\u8b70\uff08\u517c \u56fd\u969b\u4f1a\u8b70\uff09\uff08\u6de1\u8def\u5922\u821e\u53f0\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>2015\u5e749\u67081~5\u65e5\u3000 Cold Spring Harbor Meeting &#8220;EUKARYOTIC DNA REPLICATION\u00a0AND GENOME MAINTENANCE&#8221;\u3002<a href=\"http:\/\/meetings.cshl.edu\/meetings\/2015\/dnarep15.shtml\">\u60c5\u5831\u306f\u3053\u3061\u3089\u3002<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>2015\u5e749\u670811\u65e5\uff08\u91d1\uff09\u53ca\u3073\u30009\u670818\u65e5\uff08\u91d1\uff09\u30003\u9650\uff5e4\u9650\u300c\u751f\u547d\u79d1\u5b66\u7279\u5225\u8b1b\u7fa9\u300d\uff08\u5b66\u90e8\u3068\u306e\u5171\u901a\u79d1\u76ee\uff1b\u5357\u5927\u6ca2\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>2015\u5e7412\u67081~4\u65e5\u3000BMB2015\uff08\u7b2c38\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3001\u7b2c88\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a \u5408\u540c\u5927\u4f1a\uff09<br \/>\n\u795e\u6238\u30dd\u30fc\u30c8\u30a2\u30a4\u30e9\u30f3\u30c9<\/p>\n<p>&nbsp;<\/p>\n<p>\u4e0b\u8a18\u306e\u30bb\u30c3\u30b7\u30e7\u30f3\u306b\u304a\u3044\u3066\u5f53\u7814\u7a76\u5ba4\u306e\u767a\u8868\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a\u300e1W10\u300f\u300e\u30d8\u30ea\u30ab\u30eb\u30ea\u30d4\u30fc\u30c8\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u7279\u6027\u3068\u7d30\u80de\u5185\u6a5f\u80fd\u300f<br \/>\n\u65e5\u6642\uff1a2015\u5e7412\u67081\u65e5(\u706b) 9:00-11:30<br \/>\n\u4f1a\u5834\uff1a\u7b2c10\u4f1a\u5834(\u795e\u6238\u30dd\u30fc\u30c8\u30d4\u30a2\u30db\u30c6\u30eb \u5357\u9928 B1F \u30c8\u30d1\u30fc\u30ba)<br \/>\n\u5e2d\u6570\uff1a\u7d04300\u5e2d<br \/>\n\u767a\u8868\u4e88\u5b9a\u8005\uff1a\u68ee\u5c71 \u8ce2\u6cbb<\/p>\n<p>&nbsp;<\/p>\n<p>\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a\u300e1W2-p\u300f\u300e\u67d3\u8272\u4f53\u306e\u6a5f\u80fd\u30fb\u69cb\u7bc9\u539f\u7406\u300f<br \/>\n\u65e5\u6642\uff1a2015\u5e7412\u67081\u65e5(\u706b) 14:00-16:30<br \/>\n\u4f1a\u5834\uff1a\u7b2c2\u4f1a\u5834(\u795e\u6238\u30dd\u30fc\u30c8\u30d4\u30a2\u30db\u30c6\u30eb \u672c\u9928 B1F \u5055\u697d1)<br \/>\n\u5e2d\u6570\uff1a\u7d04340\u5e2d<br \/>\n\u767a\u8868\u4e88\u5b9a\u8005\uff1a\u6b63\u4e95 \u4e45\u96c4<\/p>\n<p>&nbsp;<\/p>\n<p>\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a\u300e2W13\u300f\u300e\u975eB\u578bDNA\u306e\u69cb\u9020\u30fb\u751f\u7269\u5b66\u7684\u610f\u7fa9\u3068\u305d\u306e\u751f\u4f53\u5236\u5fa1\u3078\u306e\u5fdc\u7528\u300f<br \/>\nStructures and biological functions of non-B DNA and its application for manipulation of biological systems<br \/>\n\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u30aa\u30fc\u30ac\u30ca\u30a4\u30b6\u30fc\u3000\u6b63\u4e95\u4e45\u96c4\u3000\u4e09\u597d\u5927\u8f14<br \/>\n\u65e5\u6642\uff1a2015\u5e7412\u67082\u65e5(\u6c34) 9:00-11:30<br \/>\n\u4f1a\u5834\uff1a\u7b2c13\u4f1a\u5834(\u795e\u6238\u30dd\u30fc\u30c8\u30d4\u30a2\u30db\u30c6\u30eb \u5357\u9928 B1F \u30eb\u30d3\u30fc)<br \/>\n\u5e2d\u6570\uff1a\u7d04150\u5e2d<br \/>\n\u767a\u8868\u4e88\u5b9a\u8005\uff1a\u52a0\u7d0d \u8c4a<\/p>\n<p>&nbsp;<\/p>\n<p>\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a\u300e3W12\u300f\u300eDNA\u8907\u88fd\u958b\u59cb\u3092\u5236\u5fa1\u3059\u308b\u9ad8\u6b21\u8907\u5408\u4f53\u30c0\u30a4\u30ca\u30df\u30af\u30b9\uff1a\u591a\u69d8\u6027\u3068\u666e\u904d\u6027\u300f<br \/>\n\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u30aa\u30fc\u30ac\u30ca\u30a4\u30b6\u30fc\u3000\u5347\u65b9 \u4e45\u592b\u3000\u7247\u5c71\u52c9<br \/>\n\u65e5\u6642\uff1a2015\u5e7412\u67083\u65e5(\u6728) 9:00-11:30<br \/>\n\u4f1a\u5834\uff1a\u7b2c12\u4f1a\u5834(\u795e\u6238\u30dd\u30fc\u30c8\u30d4\u30a2\u30db\u30c6\u30eb \u5357\u9928 B1F \u30c0\u30a4\u30e4\u30e2\u30f3\u30c9)<br \/>\n\u5e2d\u6570\uff1a\u7d04220\u5e2d<br \/>\n\u767a\u8868\u4e88\u5b9a\u8005\uff1a\u5c71\u5d0e \u8061\u5fd7<\/p>\n<p>&nbsp;<\/p>\n<h4>\u00a0<strong>2014\u5e74<\/strong><\/h4>\n<p>&nbsp;<\/p>\n<p>2014\u5e744\u670813-14\u65e5\u3000\u65b0\u5b66\u8853\u9818\u57df\u300c\u30b2\u30ce\u30e0\u9069\u5fdc\u300d\u73ed\u4f1a\u8b70 (\u6771\u4eac)<\/p>\n<p>2014\u5e744\u670819\u65e5\u3000\u79d1\u5b66\u6280\u8853\u9031\u9593\u7279\u5225\u884c\u4e8b\u3000\u5922\u796d\u30a8\u30f3\u30b9\u3000\u533b\u5b66\u7814\u5c55\u793a\uff08\u65e5\u672c\u79d1\u5b66\u672a\u6765\u9928\u3001\u6c5f\u6771\u533a\u9752\u6885\uff09<\/p>\n<p>2014\u5e744\u670820\u65e5\u3000\u7b2c24\u56de\u304b\u3059\u307f\u304c\u3046\u3089\u30de\u30e9\u30bd\u30f3 \u517c \u56fd\u969b\u76f2\u4eba\u30de\u30e9\u30bd\u30f3\u304b\u3059\u307f\u304c\u3046\u3089\u5927\u4f1a \u306b\u53c2\u52a0\uff08\u76ee\u6a19\u30bf\u30a4\u30e04\u6642\u959359\u520659\u79d2&#8211;\u5b9f\u969b\u306f\u751f\u304d\u3066\u5e30\u308b\u3053\u3068\uff09\u3002<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/04\/87d4ce09451d51505d64fb45b2be8ca8.pdf\">\u7d50\u679c\u306f\u3053\u3061\u3089\u3002<\/a><\/p>\n<p>2014\u5e745\u670816\u65e5\u3000\u5317\u4eac\u5927\u5b66\u306b\u3066\u8b1b\u6f14 (15-19\u65e5\u307e\u3067\u5317\u4eac\u5927\u5b66\u6559\u6388Daochun Kong\u535a\u58eb\u3092\u8a2a\u554f)\u3002<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/04\/P1090850.jpg\">\u3053\u3061\u3089\u3078\u3002<\/a><\/p>\n<p>2014\u5e745\u670821\u65e5\u3000\u6771\u4eac\u5927\u5b66\u6559\u990a\u5b66\u90e8\u5168\u5b66\u81ea\u7531\u7814\u7a76\u30bc\u30df\u30ca\u30fc\u30eb\u300c\u751f\u547d\u79d1\u5b66\u306e\u73fe\u5728\u30fb\u30d1\u30fc\u30c816\u300d\u8b1b\u7fa9\u300c\u79c1\u306e\u7814\u7a76\u6b74\uff1a\u592a\u5e73\u6d0b\u3092\u521d\u3081\u3066\u6e21\u3063\u3066\uff13\uff13\u5e74\u30fcDNA\u8907\u88fd\u306e\u539f\u7406\u3092\u63a2\u6c42\u3057\u3066\u300d<a href=\"https:\/\/www.igakuken.or.jp\/genome\/wp-content\/uploads\/2014\/04\/DSCN2151.jpg\">\u3053\u3061\u3089\u3078\u3002<\/a><\/p>\n<p>2014\u5e746\u67085-6\u65e5\u3000\u300c\u7b2c11\u56de 21\u4e16\u7d00\u5927\u8178\u83cc\u7814\u7a76\u4f1a\u300d\uff08\u5ca9\u624b\u770c\u76db\u5ca1\u5e02 \u3064\u306a\u304e\u6e29\u6cc9\u300c\u30db\u30c6\u30eb\u5927\u89b3\u300d\uff09\u306b\u53c2\u52a0\uff08\u4e16\u8a71\u4eba\uff09<\/p>\n<p>2014\u5e746\u670819-22\u65e5\u3000\u5ef6\u4e16\u5927\u5b66\u30fb\u533b\u5b66\u7814 Joint Symposium (\u5b89\u6771\u56de\u53e3\u6751\uff08\u9676\u5c71\u66f8\u9662\u304c\u3042\u3063\u305f\u6751)\uff09<\/p>\n<p>2014\u5e747\u670814-16\u65e5\u3000\u65b0\u5b66\u8853\u9818\u57df\u300c\u30b2\u30ce\u30e0\u3092\u652f\u3048\u308b\u975e\u30b3\u30fc\u30c9DNA\u9818\u57df\u306e\u6a5f\u80fd\u300d\u73ed\u4f1a\u8b70\uff08\u6e6f\u6cb3\u539f\u6e29\u6cc9\u30db\u30c6\u30eb\u3042\u304b\u306d\u3000\u3012259-0304\u3000\u795e\u5948\u5ddd\u770c\u8db3\u67c4\u4e0b\u90e1\u6e6f\u6cb3\u539f\u753a\u5bae\u4e0b705\uff09\u6b63\u4e95\u767a\u8868\u306f16\u65e5 11:25-11:50<\/p>\n<p>2014\u5e748\u670829-31\u65e5\u3000\u4e5d\u5dde\u5927\u5b66\u3000\u590f\u306e\u5b66\u751f\u7814\u7a76\u767a\u8868\u5408\u5bbf<\/p>\n<p>2014\u5e749\u670815-21\u65e5\u3000Marco Foiani\uff08Italy, Milan\uff09\u6559\u6388\u306e\u62db\u8058\u306b\u3088\u308a\u3000IFOM Foundation &#8211; F.I.R.C. Institute of Molecular Oncology Foundation\u3067\u8b1b\u6f14\uff08\u6f14\u984c\uff1aRegulation of DNA replication program in fission yeast and human cells\uff09\u3001\u53ca\u3073Sardinia\u5cf6\u3067\u958b\u50ac\u3055\u308c\u308b\u7814\u7a76\u5ba4\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u306b\u53c2\u52a0\u3002<\/p>\n<p>2014\u5e749\u670825-26\u65e5\u3000\u5927\u962a\u5927\u5b66\u86cb\u767d\u8cea\u7814\u7a76\u6240\u300c\u67d3\u8272\u4f53\u4f1d\u627f\u306e\u5206\u5b50\u80cc\u666f\uff1a\u8907\u88fd\u304b\u3089\u67d3\u8272\u4f53\u5206\u96e2\u307e\u3067\u300d\u8b1b\u6f14<\/p>\n<p>2014\u5e7410\u670815-18\u65e5\u3000\u7b2c87\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n<p>\u7247\u5c71 \u52c9\u5148\u751f\uff08\u4e5d\u5dde\u5927\u5b66\uff09\u3068\u3068\u3082\u306b\u3001\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u30b2\u30ce\u30e0\u3092\u652f\u3048\u308bDNA\u30d8\u30ea\u30ab\u30fc\u30bc\u306e\u52d5\u614b\u3092\u63a2\u6c42\u3059\u308b\u65b0\u305f\u306a\u7814\u7a76\u5c55\u958b\u300d\u3092coorgamnize (\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a3S12a;\u00a0\u958b\u50ac\u65e5\uff1a10\u670817\u65e5\uff08\u91d1\uff099:00-11:30;\u00a0\u4f1a\u5834\uff1a\u7b2c12\u4f1a\u5834[Room B-1])<\/p>\n<p>KAIST\u306eYeon-Soo Seo\u6559\u6388\u3092\u3053\u306e\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u306b\u306f\u62db\u8058\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<p>2014\u5e7411\u670817-21\u65e5\u30009th 3R Symposium (Gotemba, Shizuoka)<\/p>\n<p>Francesca Pisani\u6559\u6388(Istituto di Biochimica delle Proteine)\u53ca\u3073Francesca Carlomagno\u6559\u6388 (Universita&#8217; degli Studi di Napoli Federico II)\u304c\u30013R\u306b\u53c2\u52a0\u3055\u308c\u307e\u3059\u30023R\u306e\u524d\u5f8c\u306b\u533b\u5b66\u7814\u3067\u30bb\u30df\u30ca\u30fc\u3092\u3057\u3066\u3044\u305f\u3060\u304f\u4e88\u5b9a\u3067\u3059\u3002<\/p>\n<p>2014\u5e7411\u670825-27\u65e5\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a (\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c)<\/p>\n<p>\u5347\u65b9 \u4e45\u592b\u5148\u751f (\u5927\u962a\u5927\u5b66)\u3068\u3068\u3082\u306b\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u300c\u30b2\u30ce\u30e0DNA\u8907\u88fd\u5236\u5fa1\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\uff1a\u751f\u7269\u7a2e\u3092\u8d85\u3048\u305f\u7d71\u4e00\u50cf\u3068\u591a\u69d8\u6027\u3000(Conserved mechanisms and diversity of genome DNA replication: from bacteria to human)\u300d\u3092\u30aa\u30fc\u30ac\u30ca\u30a4\u30ba\u3002<\/p>\n<p>\u30bb\u30c3\u30b7\u30e7\u30f3\u756a\u53f7\uff1a\u300e3W5\u300f<br \/>\n\u65e5\u6642\uff1a2014\u5e7411\u670827\u65e5\uff08\u6728\uff09\u300013:15-15:45<br \/>\n\u4f1a\u5834\uff1a\u7b2c5\u4f1a\u5834\uff08\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c\u4f1a\u8b70\u30bb\u30f3\u30bf\u30fc\u30003\u968e\u3000304\uff09<\/p>\n<p>2014\u5e7411\u670830-12\u67082\u65e5\u30002014 A-IMBN\u00a0Governing Council Meeting\u304a\u3088\u3073Annual Conference (Henry Sy Auditorium, St. Luke&#8217;s Medical Center Global City, Manila, Philippines)\u306b\u53c2\u52a0\u3059\u308b\u3002<\/p>\n<p>2014\u5e7412\u670815\u65e5-12\u670817\u65e5<\/p>\n<p>\u5e83\u5cf6\u770c\u5bae\u5cf6\u53e3\u306b\u3066\u7b2c\uff13\uff12\u56de\u67d3\u8272\u4f53\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u30fb\u7b2c\uff11\uff13\u56de\u6838\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u7814\u7a76\u4f1a\u304c\u5408\u540c\u958b\u50ac\u3002<\/p>\n<div><\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"Contents1 OVERVIEW2 Short personal history of the leader3 Current<a href=\"https:\/\/www.igakuken.or.jp\/genome\/?page_id=2799\">&nbsp;&nbsp;[&#8230;\u7d9a\u304d\u3092\u8aad\u3080]<\/a>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/pages\/2799"}],"collection":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2799"}],"version-history":[{"count":9,"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/pages\/2799\/revisions"}],"predecessor-version":[{"id":3343,"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/pages\/2799\/revisions\/3343"}],"wp:attachment":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}