\u3010\u56fd\u969b\u5b66\u4f1a\uff1a\u8b1b\u6f14\u3011<\/p>\n
Daochun Kong, Hisao Masai,<\/u> Frank Uhlmann, Marco Foiani, Brenda J. Andrews Coorganizer Cold Spring Harbor Asia Conference, YEAST AND LIFE SCIENCES, June 21\u2013June 24, 2021. (on line)<\/p>\n
Hisao Masai<\/u>, Yutaka Kanoh<\/u>, Kaho Takasawa<\/u>, Daisuke Koida, Seiji Matsumoto “Roles of G4 binding and multimization of Rif1 in S phase regulation in fission yeast cells. ” Cold Spring Harbor Asia Conference YEAST AND LIFE SCIENCES, June 21\u2013June 24, 2021. Invited talk (on line)<\/p>\n
Chi-Chun Yang<\/u>, Hisao Masai<\/u> “Claspin is required for growth recovery from serum starvation through regulating the PI3K-PDK1-mTOR pathway. ” Cold Spring Harbor Asia Conference, DNA METABOLISM, GENOMIC STABILITY & HUMAN DISEASE November 22\u2013November 26, 2021. Invited talk (on line)<\/p>\n
\u3010\u62db\u5f85\u8b1b\u6f14\u3011<\/p>\n
Hisao Masai<\/u> “Positive and negative regulation of DNA replication through G-quadruplexes” Van Andel Institute, Michigan, USA, February 17, 2021 (on line\u8b1b\u6f14)<\/p>\n
\u3010\u56fd\u969b\u5b66\u4f1a\uff1a\u30dd\u30b9\u30bf\u30fc\u3011<\/p>\n
Tomohiro Iguchi<\/u>, Sayuri Ito<\/u>, Naoko Kokusho<\/u>, Yutaka Kanoh<\/u>, Kaho, Takasawa<\/u>, Kenji Moriyama<\/u>, Hiroyuki Sasanuma<\/u>, Hisao Masai<\/u>. “Mechanisms of membrane association of Rif1 and its role in<\/p>\n
replication timing regulation” Cold Spring Harbor Laboratory Meeting EUKARYOTIC DNA REPLICATION & GENOME MAINTENANCE. September 8-12, 2021 (on line)<\/p>\n
\u3010\u56fd\u5185\u5b66\u4f1a\uff1a\u62db\u5f85\u8b1b\u6f14\u3011<\/p>\n
\u7b39\u6cbc\u535a\u4e4b<\/u>\u300c\u96e3\u6cbb\u6027DNA\u5207\u65ad\u4fee\u5fa9\u6a5f\u69cb\u3068\u305d\u306e\u5236\u5fa1\u7834\u7dbb\u306b\u3088\u308b\u75be\u60a3\u767a\u75c7\u6a5f\u5e8f\u306e\u89e3\u660e\u300d\u67d3\u8272\u4f53\u5b89\u5b9a\u7dad\u6301\u7814\u7a76\u4f1a 2021\u5e748\u670830\u221231\u65e5 (on line)<\/p>\n
\u6b63\u4e95\u4e45\u96c4<\/u>\u3001\u7530\u4e2d\u5353<\/u>\u3001\u6df1\u6d25\u7406\u4e43<\/u>\u3001\u9dfa\u670b\u5b50<\/u> \u201d\u5927\u8178\u83cc\u306e\u7b2c\u4e8c\u306e\u8907\u88fd\u7d4c\u8def\u304b\u3089\u660e\u3089\u304b\u306b\u306a\u308b \u8907\u88fd\u69d8\u5f0f\u306e\u591a\u69d8\u6027\u3068\u666e\u904d\u6027\u201d \u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u300c\u30d0\u30af\u30c6\u30ea\u30a2\u7814\u7a76\u306e\u6700\u524d\u7dda\u304b\u3089\u7d10\u89e3\u304f\u8907\u88fd\u30b7\u30b9\u30c6\u30e0\u306e\u30e2\u30b8\u30e5\u30e9\u30ea\u30c6\u30a3\u300d\u65e5\u672c\u907a\u4f1d\u5b66\u4f1a \u7b2c93\u56de\u5927\u4f1a\u30012020\u5e749\u67088~10\u65e5(on line) \u62db\u5f85\u8b1b\u6f14<\/p>\n
\u6b63\u4e95\u4e45\u96c4<\/u> \u201cChromatin regulation that involves assembly of protein, lipid and DNA with a special higher-order structure\u201d \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u67d3\u8272\u4f53\u306e\u591a\u69d8\u306a\u6a5f\u80fd\u3092\u652f\u3048\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u9ad8\u6b21\u8907\u5408\u4f53\u300d\u7b2c94\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a\u30012021\u5e7411\u67084\u65e5(on line) \u62db\u5f85\u8b1b\u6f14<\/p>\n
Tomohiro Iguchi<\/u>, Sayuri Ito<\/u>, Naoko Kakusho<\/u>, Satoshi Yamazaki<\/u>, Asami Oji, Rino Fukatsu<\/u>, Ichiro Hiratani, Hiroyuki Sasanuma<\/u>, Hisao Masai<\/u> “Association of Rif1 with nuclear membrane is essential for genome-wide replication timing regulation” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3000\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u3000\u300cDNA\u69cb\u9020\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u3092\u57fa\u76e4\u3068\u3059\u308b\u30b2\u30ce\u30e0\u8907\u88fd\u3068\u7dad\u6301\u306e\u751f\u7269\u7a2e\u3092\u8d85\u3048\u305f\u5171\u901a\u539f\u7406\u300d2021\u5e7412\u67081~3\u65e5\u62db\u5f85\u8b1b\u6f14<\/p>\n
Hiroyuki Sasanuma<\/u>, Kousei Yamada, Ngo Trinh<\/u>, Hisao Masai<\/u>, Kosuke Yusa “Genetic interaction network of BRCA2 tumor suppressor gene” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3000\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u300c\u30b2\u30ce\u30e0\u5b89\u5b9a\u6027\uff1a\u305d\u306e\u7834\u7dbb\u3092\u8a98\u5c0e\u3059\u308b\u5206\u5b50\u6a5f\u69cb\u3068\u7834\u7dbb\u306b\u3088\u308a\u304a\u3053\u308b\u30b2\u30ce\u30e0\u7570\u5e38\u300d2021\u5e7412\u67081~3\u65e5\u62db\u5f85\u8b1b\u6f14<\/p>\n
\u3010\u56fd\u5185\u5b66\u4f1a\u306a\u3069\uff1a\u30dd\u30b9\u30bf\u30fc\u3011<\/p>\n
\u52a0\u7d0d\u8c4a<\/u>\u3001\u677e\u672c\u6e05\u6cbb<\/u>\u3001\u4e0a\u91ce\u52dd\u3001\u6b63\u4e95\u4e45\u96c4<\/u>\u00a0“\u5206\u88c2\u9175\u6bcd Rif1 \u306e\u904e\u5270\u767a\u73fe\u306f DNA \u8907\u88fd\u3092\u963b\u5bb3\u3057\u67d3\u8272\u4f53\u4e0d\u5747\u7b49\u5206\u914d\u3092\u8a98\u5c0e\u3059\u308b”\u7b2c 26 \u56deDNA \u8907\u88fd\u30fb\u7d44\u63db\u3048\u30fb\u4fee\u5fa9\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d5\u309a\u30002021 \u5e74 10 \u6708 22~23\u65e5\u3001\u53e3\u982d\u767a\u8868\u3000(on line)<\/p>\n
Chi-Chun Yang<\/u> and Hisao Masai<\/u> “Claspin is required for growth recovery from serum starvation through regulating the PI3K-Akt-mTOR\u00a0pathway” \u7b2c 26 \u56deDNA \u8907\u88fd\u30fb\u7d44\u63db\u3048\u30fb\u4fee\u5fa9\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d5\u309a\u30002021 \u5e74 10 \u6708 22~23\u65e5 (on line)<\/p>\n
\u4ee5\u4e0b\u306f\u3001\u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
\u9dfa\u670b\u5b50<\/u>\u3001\u7530\u4e2d\u5353<\/u>\u3001\u6b63\u4e95\u4e45\u96c4<\/u> “\u5927\u8178\u83cc\u67d3\u8272\u4f53\u306e\u7b2c\u4e8c\u306e\u8907\u88fd\u7cfb\u306b\u304a\u3051\u308b RNA-DNA hybrid \u306e\u89e3\u6790” \u7b2c 26 \u56deDNA \u8907\u88fd\u30fb\u7d44\u63db\u3048\u30fb\u4fee\u5fa9\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d5\u309a\u30002021 \u5e74 10 \u6708 22~23\u65e5 (on line)<\/p>\n
ChiChun Yang<\/u>, Hisao Masai<\/u> “Claspin is required for growth recovery from serum starvation through regulating the PI3K-Akt-mTOR pathway”<\/p>\n
Sayuri Ito<\/u>, Rino Fukatsu<\/u>, Naoko Kakusho<\/u>, Tomohiro Iguchi<\/u>, Hisao Masai<\/u> “Liquid-liquid phase separation of human Rif1-derived polypeptide” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Zhiying You<\/u>, Chi-Chun Yang<\/u>, Hisao Masai<\/u> “Regulation of DNA replication by phosphorylation and intramolecular interaction of Claspin, the replication\u00a0checkpoint mediator” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Youichi Tajima<\/u>, Hisao Masai<\/u> “Effects on tumorigenesis and gene expression alterations by cell fusion between mesenchymal stem cells and\u00a0bladder cancer cells” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a 2021\u5e7412\u67081~3\u65e5<\/p>\n
Tomohiro Iguchi<\/u>, Satoshi Yamazaki<\/u>, Tomio Ono<\/u>, Rie Ishii<\/u>, Karin Hori<\/u>, Shunsuke Kobayashi<\/u>, Hisao Masai<\/u> “The activation subunit of Cdc7, ASK(Dbf4), but not Cdc7 catalytic subunit, is essential for immune cell proliferation\u00a0and differentiation” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a 2021\u5e7412\u67081~3\u65e5<\/p>\n
Yutaka Kanoh<\/u>, Seiji Matsumoto<\/u>, Masaru Ueno, Hisao Masai<\/u> “Overexpressed Rif1 protein inhibits cell growth by inducing aberrant chromosome segregation” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a2021\u5e7412\u67081~3\u65e5<\/p>\n
Kenji Moriyama<\/u>, Hisao Masai<\/u> “Phase separation mediated by the C-terminal domain of murine Rif1, the genome-wide replication timing regulator\u00a0with G-quadruplex DNA-binding activity” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Karin Hori<\/u>, Tomohiro Iguchi<\/u>, Satoshi Yamazaki<\/u>, Tomio Ono<\/u>, Chiaki Maruyama<\/u>, Hisao Masai<\/u> “Roles\u00a0of Cdc7 kinase complex in brain development” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a 2021\u5e7412\u67081~3\u65e5<\/p>\n
Naoya Inoue<\/u>, Yue Ma, Masayuki Tera, Kazuo Nagasawa, Hisao Masai<\/u> “Generation of chemical and biological probes for detection of G-quadruplexes in vivo” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Taku Tanaka<\/u>, Tomoko Sagi<\/u>, Rino Fukatsu<\/u>, Yasumasa Nishito<\/u>, Hisao Masai<\/u> “The multi-replicon mode of the\u00a0Escherichia colichromosome replication: a potential role of RNA-DNA hybrid\/G4\u00a0structure” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Kaho Takasawa<\/u>, Yutaka Kanoh<\/u>, Seiji Matsumoto<\/u>, Rino Fukatsu<\/u>, Naoko Kakusho<\/u>, Huilin Li, Daisuke Kohda, Hisao Masai<\/u>“Analysis of the role of Rif1 multimerization and G4 binding in controlling replication timing” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n
Tomoko Sagi<\/u>, Taku Tanaka<\/u>, Yutaka Kanoh<\/u>, Hisao Masai<\/u> “Identification and analyses of RNA-DNA hybrids and G-quadruplex structures in Escherichia coli<\/em> and Schizosaccharomyces pombe<\/em> cells” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n Hiroyuki Sasanuma<\/u>, Kousei Yamada, Ngo Trinh<\/u>, Hisao Masai<\/u>, Kosuke Yusa “Genetic interaction network of BRCA2 tumor suppressor gene” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n Mayu Tatara, Mayuka Funakoshi, Ryo Sugiyama, Ippo Nakata, Keigo Araki, Tomohiro Iguchi<\/u>, Hisao Masai<\/u>, Hisato Kobayashi, Satoshi Namekawa, So Maezawa “Dynamic changes of chromatin accessibility during meiosis in mouse spermatogenesis” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n Ryo Sugiyama, Mayu Tatara, Keigo Araki, Ippo Nakata, Tomohiro Iguchi<\/u>, Hisao Msai<\/u>, Satosi Namekawa, So Maezawa “Dynamic nuclear lamina-chromatin interactions during spermatogenesis” \u7b2c44\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30002021\u5e7412\u67081~3\u65e5<\/p>\n Hao-Wen Hsiao<\/u>, Hisao Masai<\/u> “Role of Claspin, a DNA Replication Checkpoint Mediator, in Differentiation and Cell Cycle Progression of CD4+ T Cells” 2021\u5e74\u5ea6 \u5148\u7aef\u30e2\u30c7\u30eb\u52d5\u7269\u652f\u63f4 \u82e5\u624b\u652f\u63f4\u6280\u8853\u8b1b\u7fd2\u4f1a\u30002021\u5e749\u6708 6\u65e5 (on line)<\/p>\n Tomohiro Iguchi<\/u>, Karin Hori<\/u>, Tomio Ono<\/u>, Rie Ishii<\/u>, Satoshi Yamazaki<\/u>, Hisao Masai<\/u> “Neural stem cell- or Hematopoietic stem cell-specific knockout of Cdc7 or ASK(Dbf4) exhibits common and distinct phenotypes” 2021\u5e74\u5ea6 \u5148\u7aef\u30e2\u30c7\u30eb\u52d5\u7269\u652f\u63f4 \u82e5\u624b\u652f\u63f4\u6280\u8853\u8b1b\u7fd2\u4f1a\u30002021\u5e749\u6708 6\u65e5 (on line)<\/p>\n","protected":false},"featured_media":0,"template":"","_links":{"self":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/topics\/3120"}],"collection":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/topics"}],"about":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=\/wp\/v2\/types\/topics"}],"wp:attachment":[{"href":"https:\/\/www.igakuken.or.jp\/genome\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}