Tokyo Metropolitan Institute of Medical Science: Laboratory of Protein Metabolism

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Position Name Project
Project Leader Yasushi Saeki, Ph.D. Elucidation of the basic mechanism of ubiquitin-proteasome system
Project Supervisor Keiji Tanaka, Ph.D.
(The Chairperson of TMiMS)
Analysis of the immuno-type proteasomes
Emeritus Researcher Hiromichi Yonekawa, Ph.D. Pathophysiological analysis of proteasome mutant mice
Staff Scientist Akinori Endo, Ph.D. Characterization of ubiquitin-proteasome system by proteomics
Staff Scientist Hikaru Tsuchiya, Ph.D. Characterization of ubiquitin decoders for proteasomal degradation
Staff Scientist Takuya Tomita, Ph.D. Elucidation of the regulatory mechanism of proteasomal degradation
Technical Staff Naoko Arai Functional analysis of proteasome-interacting proteins
Technical Staff Sayaka Ono Technical improvement of in-depth quantitative proteomics
Technical Staff Yasuko Kawase Evaluation of chemical tools for ubiquitin research
Cooperative Researcher Fumiaki Ohtake, Ph.D.
(Hoshi University)
Identification and characterization of novel ubiquitin codes
Cooperative Researcher Yosuke Demizu, Ph.D.
Development of chemical tools for UPS researches
Cooperative Researcher Sayaka Yasuda, Ph.D.
(on an overseas assignment)
Spatio-temporal dynamics of the proteasome in vivo
Graduate Student Kenta Kisaï Substrate selectivity of ubiquitin decoders of proteasome pathway
Graduate Student Miho Sakuma Characterization of ubiquitin-independent proteasomal substrates
Visiting Student Kota Nakadai Proteomics analysis of target-interacting proteins by in-cell proximal labeling
Visiting Student Dai Nakamura Characterization of atypical ubiquitin chains
Secretary Kyoko Ueda
Secretary Harumi Seto