Tokyo Metropolitan Institute of Medical Science: Laboratory of Protein Metabolism

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Apr 1st, 2021 Members and Publications update.
Apr 1st, 2021 Dr. Saeki has become a visiting professor at the University of Tokyo.
Mar 19th, 2021 Kotani-Kun received the Excellent Research Award from CBMS, the Univ of Tokyo. Congratulations!
Feb 10th, 2021 A collaborative paper with Dr. Ohtake (Hoshi University) on TRIP12-induced neo-substrate degradation is out in Mol Cell. Congratulations!
June 23th, 2020 Dr. Tsuchiya's review on the mechanisms of proteasomal degradation is out in Pharmaceuticals.
Apr 1st, 2020 Protein Metabolism Project has started (renamed from Laboratory of Protein Metabolism).
Feb 20th, 2020 Dr. Tsuchiya received the Welfare and Health Bureau Director Award from Tokyo Metropolitan Government.
Feb 5th, 2020 Dr. Yasuda's paper on the LLPS of proteasomes is published in Nature. Congratulations!
Dec 13th, 2019 Dr. Tsuchiya's paper, a collaborative research with Dr. Fukai (The Univ of Tokyo), on the p97 cofactor Npl4-Ufd1 is published in Nat Commun.
Dec 1st, 2019 Dr. Ohtake moved to Hoshi University as an Associate Professor. Congratulations!
Nov 20th, 2019 Dr. Keiji Tanaka, the Chairperson of TMiMS, was chosen as "Highly Cited Researchers 2019" by Clarivate Analytics.
Apr 15th, 2019 Member update.
Apr 15th, 2019 Publications update.
Feb 22th, 2019 Dr. Ohtake received the Igakuken Research Award 2018.
Aug 13th, 2018 Dr. Tanaka's review on immuno- and thymo-proteasomes is out in Nature Immunol.
Jul 1st, 2018 Grant-in-Aid for Scientific Research on Innovative Areas "Ubiquitin New Frontier Driven by Chemo-technologies" has started.
Apr 12th, 2018 A collaborative paper with Dr. Komada (Tokyo Institute of Technology) on deubiquitylating enzymes and stress granules has been published in J Cell Sci. Congratulations Ms. Xie!
Feb 6th, 2018 Dr. Tsuchiya's paper on Ubiquitin chain length determination method has been published in Nat Commun.
Jan 30th, 2018 Dr. Ohtake's paper on K48/K63-branched chains has been published in PNAS.
Dec 13th, 2017 Dr. Keiji Tanaka, the chairperson of TMiMS, received the Japan Medical Research and Development Grand Prize from the Prime Minister Shinzo Abe.
Oct 19th, 2017 A collaborative paper with Prof. Nakanishi (Tokyo Univ.) on histone H3 ubiquitylation has been published in Mol Cell.
Sep 25th, 2017 A collaborative paper with Prof. Fukai (Tokyo Univ.) on USP30 structure has been published in NSMB.
Jul 31th, 2017 A collaborative paper with Prof. Inada (Tohoku Univ.) on ribosome ubiquitylation has been published in Nature Commun.
Jul 25th, 2017 Dr. Yoshida's paper on lysophagy has been published in PNAS.
May 18th, 2017 Dr. Tsuchiya's paper on yeast ubiquitin decoder proteins has been published in Mol Cell.
Apr 1st, 2017 Ms. Kawano joined our lab.
Nov 29th, 2016 Dr. Aaron Ciechanover (Technion - Israel Institute of Technology) and Dr. Chin Ha Chung (Seoul National University) visited our lab. Thank you for the stimulating lectures.
Oct 20th, 2016 Dr. Ohtake's paper on K48/K63-branched ubiquitin chains has been published in Mol Cell.
Aug 17th, 2016 A collaborative paper with Dr. K.Rock (UMass) on immuno-proteasomes has been published in Nature Immunol.
Jun 27th, 2016 A collaborative paper with Dr. Komatsu (Niigata Unv.) on p62 and hepatocellular carcinoma has been published in Nature Commun.
Apr. 2016 Publications update.
Apr. 2016 Dr. Fumiaki Ohtake and Dr. Sayaka Yasuda joined our lab.
Dec. 2015 Dr. Hikaru Tsuchiya received the best poster award in the 2nd meeting of the Ubiquitin Neobiology.
Dec. 2014 This new web site was released.
Nov. 2014 Dr. Hidehito Yoshihara wins the Poster Prize in ZOMES VIII.
Nov. 2014 Prof. Keiji Tanaka is selected for the Person of Cultural Merit in Japan.
Oct. 2014 Dr. Yasushi Saeki is selected for the Young Investigator Award from the Japanese Biochemical Society.
Oct. 2014 Dr. Hidehito Yoshihara is selected the Young Investigators Award from JSPP 2014.
May 2014 Our collaborative study of the phospho-ubiquitin with Dr. Noriyuki Matsuda was published in Journal ‘Nature’.
Apr. 2014 Drs. Noriyuki Matsuda and Yukiko Yoshida moved to the Protein Metabolism Project in Tokyo Metropolitan Institute of Medical Science.
Apr. 2014 Dr. Yoko Kimura was promoted to a professor in Shizuoka University.
(http://www.agr.shizuoka.ac.jp/abc/envstress/index_en.html)
Mar. 2014 Our study of spatio-temporal dynamics of the proteasome was published in ‘Nature Communication’.
Aug. 2013 Mr. Hikaru Tsuchiya is selected the Young Investigators Award from JSPP 2013.
Jul. 2013 Prof. Keiji Tanaka organized the 35th Naito Conference on “The Ubiquitin-Proteasome System: From Basic Mechanisms to Pathophysiological Roles” in Sapporo, Japan.
Jul. 2013 Prof. Keiji Tanaka organized the 4th IGAKUKEN International Symposium on “Cutting-edge of the Ubiquitin-Proteasome System (UPS)” in Tokyo, Japan.
Apr. 2013 Dr. Yasushi Saeki received the Young Scientists’ Prize, the Commendation for Science and Technology by MEXT.