Calpain is an enzyme that regulates cells and thus, biological organisms, by separating various intracellular proteins and converting their function and structure. For this reason, interruption to the effective working of calpain will lead to the incidence of various diseases, such as muscular dystrophy and bleeding stomach.
This project indicates directions for the diagnosis and treatment of disease by analyzing how calpain adjusts the function of cells at the molecular level and clarifying the mechanisms behind the onset of these diseases.
Project Leader Hiroyuki Sorimachi
Leader Hiroyuki Sorimachi