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論文
- タイトル
- タイトル（英）
- Incorporating tree-thinking and evolutionary time scale into developmental biology.
- 参照URL
- https://researchmap.jp/yuichirohara/published_papers/15937791
- 著者
- 著者（英）
- Shigehiro Kuraku,Nathalie Feiner,Sean D Keeley,Yuichiro Hara
- 担当区分
- 概要
- 概要（英）
- Phylogenetic approaches are indispensable in any comparative molecular study involving multiple species. These approaches are in increasing demand as the amount and availability of DNA sequence information continues to increase exponentially, even for organisms that were previously not extensively studied. Without the sound application of phylogenetic concepts and knowledge, one can be misled when attempting to infer ancestral character states as well as the timing and order of evolutionary events, both of which are frequently exerted in evolutionary developmental biology. The ignorance of phylogenetic approaches can also impact non-evolutionary studies and cause misidentification of the target gene or protein to be examined in functional characterization. This review aims to promote tree-thinking in evolutionary conjecture and stress the importance of a sense of time scale in cross-species comparisons, in order to enhance the understanding of phylogenetics in all biological fields including developmental biology. To this end, molecular phylogenies of several developmental regulatory genes, including those denoted as "cryptic pan-vertebrate genes", are introduced as examples.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Development, growth & differentiation
- 巻
- 58
- 号
- 1
- 開始ページ
- 131
- 終了ページ
- 42
- 出版年月
- 2016年1月
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- ISSN
- 0012-1592
- DOI URL
- https://doi.org/10.1111/dgd.12258
- 共同研究・競争的資金等の研究課題
研究者
原 雄一郎
( )