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論文
- タイトル
- タイトル（英）
- Single-unit Recording in Awake Behaving Non-human Primates
- 参照URL
- https://researchmap.jp/Masafumi_Nejime/published_papers/32544673
- 著者
- 著者（英）
- Mengxi Yun,Masafumi Nejime,Masayuki Matsumoto
- 担当区分
- 概要
- 概要（英）
- Non-human primates (NHPs) have been widely used as a species model in studies to understand higher brain functions in health and disease. These studies employ specifically designed behavioral tasks in which animal behavior is well-controlled, and record neuronal activity at high spatial and temporal resolutions while animals are performing the tasks. Here, we present a detailed procedure to conduct single-unit recording, which fulfils high spatial and temporal resolutions while macaque monkeys (i.e., widely used NHPs) perform behavioral tasks in a well-controlled manner. This procedure was used in our previous study to investigate the dynamics of neuronal activity during economic decision-making by the monkeys. Monkeys' behavior was quantitated by eye position tracking and button press/release detection. By inserting a microelectrode into the brain, with a grid system in reference to magnetic resonance imaging, we precisely recorded the brain regions. Our experimental system permits rigorous investigation of the link between neuronal activity and behavior.
- 出版者・発行元
- 出版者・発行元（英）
- Bio-Protocol, LLC
- 誌名
- 誌名（英）
- BIO-PROTOCOL
- 巻
- 11
- 号
- 8
- 開始ページ
- e3987
- 終了ページ
- 出版年月
- 2021年
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 2331-8325
- DOI URL
- https://doi.org/10.21769/bioprotoc.3987
- 共同研究・競争的資金等の研究課題
研究者
禰占 雅史
( )