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論文
- タイトル
- タイトル（英）
- In situ estimation of optical properties of rat and monkey brains using femtosecond time-resolved measurements.
- 参照URL
- https://researchmap.jp/SleepLab/published_papers/30760735
- 著者
- 著者（英）
- Yoko Hoshi,Yukari Tanikawa,Eiji Okada,Hiroshi Kawaguchi,Masahito Nemoto,Kosuke Shimizu,Tohru Kodama,Masataka Watanabe
- 担当区分
- 概要
- 概要（英）
- An accurate knowledge of tissue optical properties (absorption coefficients, μa, and reduced scattering coefficients, μs') is critical for precise modeling of light propagation in biological tissue, essential for developing diagnostic and therapeutic optical techniques that utilize diffusive photons. A great number of studies have explored the optical properties of various tissue, and these values are not known in detail due to difficulties in the experimental determination and significant variations in tissue constitution. Especially, in situ estimates of the optical properties of brain tissue, a common measurement target in optical imaging, is a challenge because of its layer structure (where the thin gray matter covers the white matter). Here, we report an approach to in situ estimates of the μa and μs' of the gray and white matter in living rat and monkey brains by using femtosecond time-resolved measurements and Monte Carlo simulation. The results demonstrate that the μa of the gray matter is larger than that of the white matter, while there was no significant difference in the μs' between the gray and white matter. The optical properties of the rat brain were very similar to those of the monkey brain except for the μa of the gray matter here.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Scientific reports
- 巻
- 9
- 号
- 1
- 開始ページ
- 9165
- 終了ページ
- 9165
- 出版年月
- 2019年6月24日
- 査読の有無
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.1038/s41598-019-45736-5
- 共同研究・競争的資金等の研究課題
研究者
児玉 亨
( )