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論文
- タイトル
- タイトル（英）
- Atomic force microscopy observation of membrane proteins suspended over carbon nanotube network
- 参照URL
- https://researchmap.jp/read0091842/published_papers/27448519
- 著者
- 著者（英）
- Koji Sumitomo,Youichi Shinozaki,Daisuke Takagi,Hiroshi Nakashima,Yoshihiro Kobayashi,Keiichi Torimitsu
- 担当区分
- 概要
- 概要（英）
- Atomic force microscopy (AFM) imaging of membrane proteins suspended over a nanostructure in liquid is a promising way to understand the structure and function of working proteins, although the membrane deformation that occurs during scanning makes it difficult to obtain a high resolution image. This study proposes an artificial cell system for the AFM observation of functional membrane proteins that consists of a sub-micron well on Si, a biological membrane, and a carbon nanotube (CNT) network. We successfully observed molecular-scale images of a purple membrane suspended over sub-micron well patterns. By using a CNT network to hold the suspended membrane, we suppressed the membrane deformation caused by the "imaging force". The CNT network takes the place of a cytoskeleton in supporting the cell membrane suspended over the well thus improving the spatial resolution of AFM measurement. © 2009 The Japan Society of Applied Physics.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Japanese Journal of Applied Physics
- 巻
- 48
- 号
- 8
- 開始ページ
- 終了ページ
- 出版年月
- 2009年8月
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 0021-4922,1347-4065
- DOI URL
- https://doi.org/10.1143/JJAP.48.08JB18
- 共同研究・競争的資金等の研究課題
研究者
篠﨑 陽一
(シノザキ ヨウイチ)