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Development of Stem Cell-based Blood Regeneration Techniques for Cancer Therapy

Project Leader Takahiko Hara

Takahiko Hara

Recent research topics

Topic 1

Enforced expression of Lhx2 leads to robust ex vivo production of HSC-like cells from mouse ESCs/iPSCs.

Topic 2

Lhx2 induces degradation of Lmo2 protein, thereby inhibiting proliferation of human T-cell acute lymphoblastic leukemia (T-ALL) cells.

Topic 3

CXCL14 is one of the tuning molecules for CXCL12/CXCR4 signaling axis.