Cells are the fundamental units of all living organisms. In this project, we study the molecular mechanisms of “Intracellular quality control.”
For example, cells contain various structures called organelles, which are enclosed by biological membranes and play essential roles such as energy production, protein synthesis and transport, and the modification of biomolecules.
In recent years, it has become clear that the accumulation of stressed or malfunctioning organelles and proteins—analogous to defective products in a factory—can impair cellular functions and contribute to disease pathogenesis such as neurodegenerative and metabolic disorders.

This is where our research on intracellular quality control becomes important. Cells possess systems to repair, degrade, and remove damaged or dysfunctional organelles and proteins.
By elucidating the molecular mechanisms underlying these quality control pathways, we aim to deepen our understanding of how cells maintain their health.
Ultimately, this knowledge may help identify the causes of disease onset and pave the way for the development of new preventive and therapeutic strategies. Our goal is to explore the quality control systems of cells—the smallest units of life—and to contribute to the realization of a healthier society.