Deciphering the Multilayered Systems of genome stability and DNA strand break repair
The conference brings together world-leading experts to explore the dynamic interplay of DNA metabolic pathways. Our mission is to foster interdisciplinary dialogue on the latest breakthroughs in DNA strand break repair and their systemic consequences, bridging the gap between fundamental science and clinical implications.
The conference will be held in Tokyo on November 13–14, 2026, following the 3R3CD Symposium in Nagasaki (November 9–12).
The 13th 3R+3C+D International Symposium 
Date
November 13–14, 2026
Venue
2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan
Tokyo Metropolitan Institute of Medical Science
Organizers
Genome Dynamics Project / Tokyo Metropolitan Institute of Medical Science
Hiroyuki Sasanuma
Hisao Masai
About
The inheritance and stable maintenance of the genome are essential for the survival and homeostasis of living organisms. Disruption of these processes leads to diseases, including cancer. In particular, systems that repair damage arising in the genome from both endogenous and exogenous causes represent one of the most critical strategies by which organisms protect their genomes, and defects in these systems are major causes of diseases such as cancer.
This international symposium will bring together leading researchers from abroad who are at the forefront of studies on the mechanisms of genome inheritance and maintenance—such as DNA repair and recombination—and their relationships to disease. Through presentations of the latest findings, the symposium will provide a forum for discussion of the remaining challenges and future perspectives in the field. The symposium will offer a valuable opportunity to disseminate our institute’s discoveries on mechanisms that ensure genome stability to leading scientists worldwide, while also serving as a unique occasion to gather the most up-to-date information from this rapidly advancing field.
At this symposium, in-depth discussions will be held on the mechanisms underlying the development of diseases such as cancer, as well as on the latest insights into strategies for their prediction, prevention, and treatment. The knowledge gained is expected to provide important insights for a wide range of ongoing research at our institute, including studies on the genome, cancer, stem cell regulation, neurodegenerative diseases, and brain development, and will promote future collaborations.
News
- 2026/04/28 Program page open.
- 2026/04/28 New website opened.
Support
sponsored by Yamada Science Foundation
Contact
33rd TMIMS International Symposium
mail：sasanuma-hr（
）igakuken.or.jp