The Tokyo Metropolitan Institute of Medical Science (TMIMS) was established in 2011 from the merger of the Tokyo Metropolitan Institute of Psychiatry, the Tokyo Metropolitan Institute for Neuroscience, and the Tokyo Metropolitan Institute of Medical Science. Its mission is to conduct research on critical unresolved diseases, including neurological disorders, mental illnesses, cancers, and infectious diseases, and to disseminate the results toward the improvement of medical care and the welfare of Tokyo residents. Since its establishment, TMIMS has steadily accumulated achievements across a wide range of research fields in basic, clinical, and social medicine.

In Tokyo, the percentage of people aged 65 and older is projected to reach 23.4% by 2025, and the population of late-stage elderly individuals aged 75 and older is expected to increase through 2045. As the elderly population grows, the number of patients suffering from dementias, cancers, heart diseases, and other conditions will likely increase. Simultaneously, modern stress-laden societies have seen rising cases of mental illness, and the renewed importance of infectious disease control—highlighted by the impact of the COVID-19 pandemic—underscores the multifaceted challenges facing the health of Tokyo residents. To address these issues and respond to public needs, TMIMS actively conducts cutting-edge research aimed at overcoming diverse diseases. By applying the results of this research to society, TMIMS contributes to prolonging healthy life expectancy and enhancing the quality of life (QOL) of Tokyo residents.

In 2025, we began our 5th Project Term, consisting of 17 Project Research Programs supported for a five-year term. These projects fall into 10 key topics, including Genomics and Cancers, and Dementia and Neurodegenerative Diseases. Furthermore, TMIMS includes three research centers, for genome and medical sciences, social sciences and medicine, and infectious diseases. These research centers contribute directly to Tokyo’s health, medical care, and welfare policies. In addition, as a Tokyo-based research institute, TMIMS collaborates with metropolitan hospitals, universities, and other research organizations, fostering joint research projects and developing partnerships through the exchange of research personnel.

TMIMS is committed to pursuing research that leads to innovative strategies for disease prevention, diagnosis, and treatment. By delivering world-class discoveries from Tokyo to the global scientific community, we aim not only to improve the lives of Tokyo residents but also to contribute to the health and well-being of people around the world.