笹沼 博之
Hiroyuki Sasanuma

プロジェクトリーダー

mail：sasanuma-hr

Hiroyuki’s research focuses on the molecular mechanisms involved in the repair of DNA double-strand breaks. He uses yeast, human cell lines, and mice as model organisms. He currently conducts experiments both at the bench and in the culture room, similar to a postdoctoral researcher. Hiroyuki is particularly interested in developing new therapies to cure cancer. His hobbies include reading books and listening to music. He also loves skiing and visits the Zao Ski Resort in Yamagata alone every year.

正井 久雄
Hisao Masai

mail：masai-hs

過去の情報はこちらからご覧ください

北島 健二
Kenji Kitajima

Kenji is an expert in stem cell research, with a particular focus on hematopoietic stem cells. His primary interest lies in uncovering the molecular mechanisms that link genome instability to the regulation of hematopoiesis.

種子島 幸祐
Kosuke Tanegashima

Kosuke stands at the forefront of immunology and molecular biology, drawing on his extensive expertise in tumor immunology, DNA sensing, and chemokine research. His work focuses on unraveling the molecular mechanisms that improve the effectiveness of cancer immunotherapy and contribute to the development of novel therapeutic strategies.

平井 隼人
Hayato Hirai

After earning his doctorate in yeast genetics, Hayato is now engaged in cancer research using mouse models. He is particularly interested in establishing experimental systems to prospectively study the early stages of tumorigenesis. His research currently focuses on how cellular nutritional status influences chromatin structure, as well as DNA repair and replication leading to tumorigenesis.

山田 真太郎
Shintaro Yamada

Shintaro Yamada wants to understand how cells repair DNA efficiently. Radiation and other naturally occurring exogenous and endogenous DNA damaging agents often generate genomic DNA breaks with chemically modified DNA ends that are highly carcinogenic. Cleaning the modified DNA ends is a critical step of DNA repair, but much remains unknown about its molecular mechanism. To understand this process, Yamada is developing high-resolution methods and examining how DNA repair machinery works at DNA break ends and prevents cancer-causing genetic mutations in human cells.

加納 豊
Yutaka Kanoh

Yutaka specializes in the advancement of next-generation sequencing (NGS) technologies. His research is particularly focused on developing innovative experimental platforms for the sensitive detection of specific DNA lesions and strand breaks, employing DNA isolated from yeast, human cells, and mouse tissues.

井口 智弘
Tomohiro Iguchi

After earning his doctorate in immunology, Tomo has focused on investigating the cellular immune mechanisms that maintain chromosomal stability. He is currently interested in how the molecular mechanisms of DNA replication and repair differ across organs and during development, using mouse models in his research.

高井 裕子
Zhiying You

高井さんは、DNA複製ヘリカーゼMCMと複製フォーク安定化因子Claspinタンパク質のDNA複製の開始と進行における機能解析という課題に取り組んでいます。最近の彼女の興味は、Claspinのリン酸化による複製フォーク複合体の活性制御の解明を目指して研究しています。
彼女の趣味は音楽鑑賞と旅行です。

田中 卓
Taku Tanaka

Taku is conducting research on the mechanisms of DNA replication in Escherichia coli. His focus is on identifying the cis-acting sequences and trans-acting factors involved in transcription-dependent DNA replication, which differs from typical modes of DNA replication.

田島 陽一
Youichi Tajima

柴田 武彦
Takehiko Shibata

伊藤 さゆり
Sayuri Ito