論文

2022年

  • Yasuda SP, Miyasaka Y, Hou X, Obara Y, Shitara H, Seki Y, Matsuoka K, Takahashi A, Wakai E, Hibino H, Takada T, Shiroishi T, Kominami R, Kikkawa Y: Two loci contribute to age-related hearing loss resistance in the Japanese wild-derived inbred MSM/Ms mice. Biomedicines, 10, 2221, 2022. [PubMed]
  • Miura I, Kikkawa Y, Yasuda SP, Shinogi A, Usuda D, Kumar V, Takahashi JS, Tamura M, Masuya H, Wakana S: Characterization of single nucleotide polymorphisms for forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice. Exp Anim, 71, 240-251, 2022. [PubMed]
  • 関 優太吉川欣亮:難聴の遺伝的要因と発症メカニズム.医学のあゆみ,282, 648-656, 2022.
  • 吉川欣亮関 優太安田俊平:ミオシンVIハプロ不全に起因する加齢性難聴.バイオサイエンスとインダストリー,80, 301-305, 2022.
  • 吉川欣亮:聴覚と遺伝子.遺伝学の百科事典,267-277, 2022.

2021年

  • Seki Y, Shitara H, Ishii R, Ouchi T, Yasuda SP and Kikkawa Y: Myosin VI Haploinsufficiency Reduced Hearing Ability in Mice. Neuroscience, 478, 100-111, 2021. [PubMed]
  • Balan S, Ohnishi T, Watanabe A, Ohba H, Iwayama Y, Toyoshima M, Hara T, Hisano Y, Miyasaka Y, Toyota T, Shimamoto-Mitsuyama C, Maekawa M, Numata S, Ohmori T, Shimogori T, Kikkawa Y, Hayashi T and Yoshikawa T: Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and implication of CDH23 in schizophrenia. Schizophr Bull, 47, 1190-1200, 2021. [PubMed]

2020年

  • Yasuda SP, Seki Y, Suzuki S, Ohshiba Y, Hou X, Matsuoka K, Wada K, Shitara H, Miyasaka Y and Kikkawa Y: c.753A>G genome editing of a Cdh23ahl allele delays age-related hearing loss and degeneration of cochlear hair cells in C57BL/6J mice. Hear Res, 389, 107926, 2020. [PubMed]

2019年

  • Matsuoka K, Wada K, Miyasaka Y, Yasuda SP, Seki Y, Nishito Y, Yonekawa H, Taya C, Shitara H and Kikkawa Y: OHC-TRECK: A novel system using a mouse model for investigation of the molecular mechanisms associated with outer hair cell death in the inner ear. Sci Rep, 9, 5285, 2019. [PubMed]

2018年

  • Yasuda SP, Miyasaka Y and Kikkawa Y: Effects of genetic background on susceptibility and the acceleration of hearing loss in mice. An Excursus into Hearing Loss (Edited by: S. Hatzopoulos and A. Ciorba), IntechOpen, London., UK, pp. 3–23, 2018 [Book]

2017年

  • Seki Y, Miyasaka Y, Suzuki S, Wada K, Yasuda SP, Matsuoka K, Ohshiba Y, Endo K, Ishii R, Shitara H, Kitajiri SI, Nakagata N, Takebayashi H and Kikkawa Y: A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells. PLoS One, 12, e0183477, 2017. [PubMed]

2016年

  • Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami K, Yonekawa H and Kikkawa Y: Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23. Hum Mol Genet, 25, 2045-2059, 2016. [PubMed]
  • Kikkawa Y and Miyasaka Y: Genetic modifiers of hearing loss in mice: The case of phenotypic modification in homozygous Cdh23ahl age-related hearing loss. Monographs in Human Genetics –Genetics of Deafness– (Edited by: B. Vona & T. Haaf), Karger Publishers, Basel, Switzerland, 20, pp 97–109, 2016. [Book]

2015年

  • Uetsuka S, Ogata G, Nagamori S, Isozumi N, Nin F, Yoshida T, Komune S, Kitahara T, Kikkawa Y, Inohara H, Kanai Y and Hibino H: Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea. Eur J Neurosci, 42, 1984-2002, 2015. [PubMed]
  • Suzuki S, Ishikawa M, Ueda T, Ohshiba Y, Miyasaka Y, Okumura K, Yokohama M, Taya C, Matsuoka K and Kikkawa Y: Quantitative trait loci on chromosome 5 for susceptibility to frequency-specific effects on hearing in DBA/2J mice. Exp Anim, 64, 241-251, 2015. [PubMed]

2014年

  • Nakajima M, Nishikawa C, Miyasaka Y, Kikkawa Y, Mori H, Tsuruta M, Okuyama S and Furukawa Y: Dilation of the inferior colliculus and hypersensitivity to sound in Wnt1-cre and Wnt1-GAL4 double-transgenic mice. Neurosci Lett, 566, 236-240, 2014. [PubMed]

2013年

  • Miyasaka Y, Suzuki S, Ohshiba Y, Watanabe K, Sagara Y, Yasuda SP, Matsuoka K, Shitara H, Yonekawa H, Kominami R and Kikkawa Y: Compound heterozygosity of the functionally null Cdh23v-ngt and hypomorphic Cdh23ahl alleles leads to early-onset progressive hearing loss in mice. Exp Anim, 62, 333-346, 2013. [PubMed]

2012年

  • Kikkawa Y, Seki Y, Okumura K, Ohshiba Y, Miyasaka Y, Suzuki S, Ozaki M, Matsuoka K, Noguchi Y and Yonekawa H: Advantages of a mouse model for human hearing impairment. Exp Anim, 61, 85-98, 2012. Review. [PubMed]

2011年

  • Dang R, Torigoe D, Suzuki S, Kikkawa Y, Moritoh K, Sasaki N and Agui T: Genetic background strongly modifies the severity of symptoms of Hirschsprung disease, but not hearing loss in rats carrying Ednrbsl mutations. PLoS One, 6, e24086, 2011. [PubMed]

2010年

  • Mburu P, Romero M, Hilton H, Parker A, Townsend S, Kikkawa Y and Brown SDM: Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia. PLoS One, 5, e11627, 2010. [PubMed]
  • Mochizuki E, Okumura K, Ishikawa M, Yoshimoto S, Yamaguchi J, Seki Y, Wada K, Yokohama M, Ushiki T, Tokano H, Ishii R, Shitara H, Taya C, Kitamura K, Yonekawa H and Kikkawa Y: Phenotypic and expression analysis of a novel spontaneous Myosin VI null mutant mouse. Exp Anim, 59, 57-71, 2010. [PubMed]
  • Okumura K, Mochizuki E, Yokohama M, Yamakawa H, Shitara H, Mburu P, Yonekawa H, Brown SD and Kikkawa Y: Protein 4.1 expression in the developing hair cells of the mouse inner ear. Brain Res, 1307, 53-62, 2010. [PubMed]