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Research Article

2024

  1. "Yamazaki K, Iguchi T, Kanoh Y, Takayasu K, Ngo TTT, Onuki A, Kawaji H, Oshima S, Kanda T, Masai H, Sasanuma H.",Homologous recombination contributes to the repair of acetaldehyde-induced DNA damage,Cell Cycle. 2024 Feb;23(4):369-384. doi: 10.1080/15384101.2024.2335028. Epub 2024 Apr 3.,2024
  2. "Biller M, Kabir S, Boado C, Nipper S, Saffa A, Tal A, Allen S, Sasanuma H, Dréau D, Vaziri C, Tomida J.",REV7-p53 interaction inhibits ATM-mediated DNA damage signaling,Cell Cycle. 2024 Feb;23(4):339-352. doi: 10.1080/15384101.2024.2333227. Epub 2024 Apr 1.,2024
  3. "Shibata T, Ikawa S, Iwasaki W, Sasanuma H, Masai H, Hirota K.",Homology recognition without double-stranded DNA-strand separation in D-loop formation by RecA,Nucleic Acids Res. 2024 Mar 21;52(5):2565-2577. doi: 10.1093/nar/gkad1260.,2024
  4. "Charlton SJ, Flury V, Kanoh Y, Genzor AV, Kollenstart L, Ao W, Brøgger P, Weisser MB, Adamus M, Alcaraz N, Delvaux de Fenffe CM, Mattiroli F, Montoya G, Masai H, Groth A, Thon G.",The fork protection complex promotes parental histone recycling and epigenetic memory,Cell. 2024 Sep 5;187(18):5029-5047.e21. doi: 10.1016/j.cell.2024.07.017. Epub 2024 Aug 1.,Cell,2024,2024/08/02,10.1016/j.cell.2024.07.017
  5. "You Z, Masai H.","Assembly, Activation, and Helicase Actions of MCM2-7: Transition from Inactive MCM2-7 Double Hexamers to Active Replication Forks",Biology (Basel). 2024 Aug 17;13(8):629. doi: 10.3390/biology13080629.,Biology (Basel),2024,2024/08/28,10.3390/biology13080629
  6. "Tajima Y, Shibasaki F, Masai H.",Cell fusion upregulates PD-L1 expression for evasion from immunosurveillance,Cancer Gene Ther. 2024 Jan;31(1):158-173. doi: 10.1038/s41417-023-00693-0. Epub 2023 Nov 21.,Cancer Gene Ther,2024,2023/11/22,10.1038/s41417-023-00693-0
  7. "Kim S, Yamada S, Li T, Canasto-Chibuque C, Kim JH, Marcet-Ortega M, Xu J, Eng DY, Feeney L, Petrini JHJ, Keeney S.",The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse, bioRxiv. 2024 Aug 17:2024.08.17.608390. doi: 10.1101/2024.08.17.608390.
  8. "Kim S, Yamada S, Maekawa K, Keeney S.",Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes,bioRxiv,2024,2024/08/16,10.1101/2024.08.10.606181

2023

  1. "Tomita A, Sasanuma H, Owa T, Nakazawa Y, Shimada M, Fukuoka T, Ogi T, Nakada S.",Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells,Nat Commun. 2023 Sep 15;14(1):5607. doi: 10.1038/s41467-023-41048-5.,2023
  2. "Sakurada-Aono M, Sakamoto T, Kobayashi M, Takiuchi Y, Iwai F, Tada K, Sasanuma H, Hirabayashi S, Murakawa Y, Shirakawa K, Sakamoto C, Shindo K, Yasunaga JI, Matsuoka M, Pommier Y, Takeda S, Takaori-Kondo A.",HTLV-1 bZIP factor impairs DNA mismatch repair system,Biochem Biophys Res Commun. 2023 May 21;657:43-49. doi: 10.1016/j.bbrc.2023.03.049. Epub 2023 Mar 21.,2023
  3. "Najnin RA, Al Mahmud MR, Rahman MM, Takeda S, Sasanuma H, Tanaka H, Murakawa Y, Shimizu N, Akter S, Takagi M, Sunada T, Akamatsu S, He G, Itou J, Toi M, Miyaji M, Tsutsui KM, Keeney S, Yamada S.",ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen,Cell Rep. 2023 Jan 31;42(1):111909. doi: 10.1016/j.celrep.2022.111909. Epub 2022 Dec 30.,2023
  4. "Akter S, Shimba A, Ikuta K, Mahmud MRA, Yamada S, Sasanuma H, Tsuda M, Sone M, Ago Y, Murai K, Tanaka H, Takeda S.",Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks,Genes Cells. 2023 Jan;28(1):53-67. doi: 10.1111/gtc.12993. Epub 2022 Dec 7.,2023
  5. "Sun W, Lee KL, Poellinger L, Masai H, Kato H.",Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types,Epigenetics. 2023 Dec;18(1):2222245. doi: 10.1080/15592294.2023.2222245.,Epigenetics,2023,2023/06/10,10.1080/15592294.2023.2222245
  6. "Hori K, Yamazaki S, Ohtaka-Maruyama C, Ono T, Iguchi T, Masai H.",Cdc7 kinase is required for postnatal brain development,Genes Cells. 2023 Oct;28(10):679-693. doi: 10.1111/gtc.13059. Epub 2023 Aug 16.,Genes Cells,2023,2023/08/16,10.1111/gtc.13059
  7. "Hsiao HW, Yang CC, Masai H.","Correction: Hsiao et al. Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses. Biomolecules 2023, 13, 125",Biomolecules. 2023 Jul 18;13(7):1145. doi: 10.3390/biom13071145.,Biomolecules,2023,2023/07/29,10.3390/biom13071145
  8. "Nemeth T, Yoshizawa-Sugata N, Pallier A, Tajima Y, Ma Y, Tóth É, Masai H, Yamakoshi Y.",Water-Soluble Gd(III)-Porphyrin Complexes Capable of Both Photosensitization and Relaxation Enhancement,Chem Biomed Imaging. 2023 May 12;1(2):157-167. doi: 10.1021/cbmi.3c00007. eCollection 2023 May 22.,Chem Biomed Imaging,2023,2023/05/26,10.1021/cbmi.3c00007
  9. "Kanoh Y, Ueno M, Hayano M, Kudo S, Masai H.",Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect,Life Sci Alliance. 2023 Feb 7;6(4):e202201603. doi: 10.26508/lsa.202201603. Print 2023 Apr.,Life Sci Alliance,2023,2023/02/07,10.26508/lsa.202201603
  10. "Hsiao HW, Yang CC, Masai H.",Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses,Biomolecules. 2023 Jan 7;13(1):125. doi: 10.3390/biom13010125.,Biomolecules,2023,2023/01/21,10.3390/biom13010125
  11. "Yang CC, Masai H.",Claspin is Required for Growth Recovery from Serum Starvation through Regulating the PI3K-PDK1-mTOR Pathway in Mammalian Cells,Mol Cell Biol. 2023 Jan;43(1):1-21. doi: 10.1080/10985549.2022.2160598.,Mol Cell Biol,2023,2023/01/31,10.1080/10985549.2022.2160598
  12. "Yoshizawa-Sugata N, Masai H.",Histone Modification Analysis of Low-Mappability Regions,Methods Mol Biol. 2023;2519:163-185. doi: 10.1007/978-1-0716-2433-3_18.,Methods Mol Biol,2023,2022/09/06,10.1007/978-1-0716-2433-3_18

2022

  1. "Nakano T, Moriwaki T, Tsuda M, Miyakawa M, Hanaichi Y, Sasanuma H, Hirota K, Kawanishi M, Ide H, Tano K, Bessho T.",SPRTN and TDP1/TDP2 Independently Suppress 5-Aza-2'-deoxycytidine-Induced Genomic Instability in Human TK6 Cell Line,Chem Res Toxicol. 2022 Nov 21;35(11):2059-2067. doi: 10.1021/acs.chemrestox.2c00213. Epub 2022 Oct 25.,2022
  2. "Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.","XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA",Genes Cells. 2022 May;27(5):331-344. doi: 10.1111/gtc.12929. Epub 2022 Mar 1.,2022
  3. Masai H.,Replicon hypothesis revisited,Biochem Biophys Res Commun. 2022 Dec 10;633:77-80. doi: 10.1016/j.bbrc.2022.09.060.,Biochem Biophys Res Commun,2022,2022/11/07,10.1016/j.bbrc.2022.09.060
  4. Masai H.,TT-pocket/HIRAN: binding to 3'-terminus of DNA for recognition and processing of stalled replication forks,J Biochem. 2022 Jul 25;172(2):57-60. doi: 10.1093/jb/mvac042.,J Biochem,2022,2022/06/06,10.1093/jb/mvac042
  5. "Nakamura H, Sekine H, Kato H, Masai H, Gradin K, Poellinger L.",Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism,J Biol Chem. 2022 Jul;298(7):102137. doi: 10.1016/j.jbc.2022.102137. Epub 2022 Jun 14.,J Biol Chem,2022,2022/06/17,10.1016/j.jbc.2022.102137

2021

  1. "Moriwaki T, Yoshimura A, Tamari Y, Sasanuma H, Takeda S, Seki M, Tano K.",PRDX1 is essential for the viability and maintenance of reactive oxygen species in chicken DT40,Genes Environ. 2021 Aug 5;43(1):35. doi: 10.1186/s41021-021-00211-4.,2021
  2. "Isobe SY, Hiraga SI, Nagao K, Sasanuma H, Donaldson AD, Obuse C.",Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action,Cell Rep. 2021 Jul 13;36(2):109383. doi: 10.1016/j.celrep.2021.109383.,2021
  3. "Kratz K, Artola-Borán M, Kobayashi-Era S, Koh G, Oliveira G, Kobayashi S, Oliveira A, Zou X, Richter J, Tsuda M, Sasanuma H, Takeda S, Loizou JI, Sartori AA, Nik-Zainal S, Jiricny J.",FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair,Mol Cell Biol. 2021 Aug 24;41(9):e0030321. doi: 10.1128/MCB.00303-21. Epub 2021 Aug 24.,2021
  4. "Xu X, Xu Y, Guo R, Xu R, Fu C, Xing M, Sasanuma H, Li Q, Takata M, Takeda S, Guo R, Xu D.",Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress,Nat Struct Mol Biol. 2021 Jun;28(6):487-500. doi: 10.1038/s41594-021-00602-9. Epub 2021 Jun 10.,2021
  5. "Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW.",XRCC1 prevents toxic PARP1 trapping during DNA base excision repair,Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7.,2021
  6. "Moribe F, Nishikori M, Takashima T, Taniyama D, Onishi N, Arima H, Sasanuma H, Akagawa R, Elloumi F, Takeda S, Pommier Y, Morii E, Takaori-Kondo A, Murai J.",Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development,PLoS One. 2021 Jan 29;16(1):e0237554. doi: 10.1371/journal.pone.0237554. eCollection 2021.,2021
  7. "Yoshizawa-Sugata N, Yamazaki S, Mita-Yoshida K, Ono T, Nishito Y, Masai H.",Loss of full-length DNA replication regulator Rif1 in two-cell embryos is associated with zygotic transcriptional activation,J Biol Chem. 2021 Dec;297(6):101367. doi: 10.1016/j.jbc.2021.101367. Epub 2021 Nov 1.,J Biol Chem,2021,2021/11/05,10.1016/j.jbc.2021.101367
  8. "Irie T, Asami T, Sawa A, Uno Y, Taniyama C, Funakoshi Y, Masai H, Sawa M.","Discovery of AS-0141, a Potent and Selective Inhibitor of CDC7 Kinase for the Treatment of Solid Cancers",J Med Chem. 2021 Oct 14;64(19):14153-14164. doi: 10.1021/acs.jmedchem.1c01319. Epub 2021 Oct 5.,J Med Chem,2021,2021/10/05,10.1021/acs.jmedchem.1c01319
  9. "Oki M, Masai H.",Regulation of HP1 protein by phosphorylation during transcriptional repression and cell cycle,J Biochem. 2021 Sep 7;169(6):629-632. doi: 10.1093/jb/mvab040.,J Biochem,2021,2021/03/27,10.1093/jb/mvab040
  10. "Nakamura K, Sakai S, Tsuyama J, Nakamura A, Otani K, Kurabayashi K, Yogiashi Y, Masai H, Shichita T.",Extracellular DJ-1 induces sterile inflammation in the ischemic brain,PLoS Biol. 2021 May 20;19(5):e3000939. doi: 10.1371/journal.pbio.3000939. eCollection 2021 May.,PLoS Biol,2021,2021/05/20,10.1371/journal.pbio.3000939
  11. "Kitajima S, Sun W, Lee KL, Ho JC, Oyadomari S, Okamoto T, Masai H, Poellinger L, Kato H.",A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition,Sci Rep. 2021 Feb 25;11(1):4538. doi: 10.1038/s41598-021-83857-y.,Sci Rep,2021,2021/02/26,10.1038/s41598-021-83857-y
  12. "Alavi S, Ghadiri H, Dabirmanesh B, Moriyama K, Khajeh K, Masai H.","G-quadruplex binding protein Rif1, a key regulator of replication timing",J Biochem. 2021 Feb 6;169(1):1-14. doi: 10.1093/jb/mvaa128.,J Biochem,2021,2020/11/10,10.1093/jb/mvaa128

2020

  1. "Rahman MM, Mohiuddin M, Shamima Keka I, Yamada K, Tsuda M, Sasanuma H, Andreani J, Guerois R, Borde V, Charbonnier JB, Takeda S.","Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination",J Biol Chem. 2020 Dec 18;295(51):17460-17475. doi: 10.1074/jbc.RA120.013521.,2020
  2. "Takeishi A, Kogashi H, Odagiri M, Sasanuma H, Takeda S, Yasui M, Honma M, Suzuki T, Kamiya H, Sugasawa K, Ura K, Sassa A.",Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells,PLoS One. 2020 Dec 31;15(12):e0244790. doi: 10.1371/journal.pone.0244790. eCollection 2020.,2020
  3. "Sasanuma H, Yamada S, Tsuda M, Takeda S.","Restoration of ligatable ""clean"" double-strand break ends is the rate-limiting step in the rejoining of ionizing-radiation-induced DNA breakage",DNA Repair (Amst). 2020 Sep;93:102913. doi: 10.1016/j.dnarep.2020.102913.,2020
  4. "Nakano T, Shoulkamy MI, Tsuda M, Sasanuma H, Hirota K, Takata M, Masunaga SI, Takeda S, Ide H, Bessho T, Tano K.",Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells,PLoS One. 2020 Jun 26;15(6):e0234859. doi: 10.1371/journal.pone.0234859. eCollection 2020.,2020
  5. "Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.",Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells,Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14412-14420. doi: 10.1073/pnas.1920165117. Epub 2020 Jun 8.,2020
  6. "Akagawa R, Trinh HT, Saha LK, Tsuda M, Hirota K, Yamada S, Shibata A, Kanemaki MT, Nakada S, Takeda S, Sasanuma H.",UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks,iScience. 2020 Apr 24;23(4):101027. doi: 10.1016/j.isci.2020.101027. Epub 2020 Mar 31.,2020
  7. "Al Mahmud MR, Ishii K, Bernal-Lozano C, Delgado-Sainz I, Toi M, Akamatsu S, Fukumoto M, Watanabe M, Takeda S, Cortés-Ledesma F, Sasanuma H.",TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands,Genes Cells. 2020 Jul;25(7):450-465. doi: 10.1111/gtc.12770. Epub 2020 May 5.,2020
  8. "Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S.",Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells,Environ Mol Mutagen. 2020 Jul;61(6):602-610. doi: 10.1002/em.22371. Epub 2020 Apr 15.,2020
  9. "Itou J, Takahashi R, Sasanuma H, Tsuda M, Morimoto S, Matsumoto Y, Ishii T, Sato F, Takeda S, Toi M.",Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition,iScience. 2020 Feb 21;23(2):100821. doi: 10.1016/j.isci.2020.100821. Epub 2020 Jan 9.,2020
  10. "Maekawa K, Yamada S, Sharma R, Chaudhuri J, Keeney S.",Triple-helix potential of the mouse genome,Proc Natl Acad Sci U S A,2022,2022/05/03,10.1073/pnas.2203967119
  11. "Yamada S, Hinch AG, Kamido H, Zhang Y, Edelmann W, Keeney S.",Molecular structures and mechanisms of DNA break processing in mouse meiosis,Genes Dev,2020,2020/05/02,10.1101/gad.336032.119

2019

  1. "Morimoto S, Tsuda M, Bunch H, Sasanuma H, Austin C, Takeda S.",Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA,Genes (Basel). 2019 Oct 30;10(11):868. doi: 10.3390/genes10110868.,2019
  2. "Sassa A, Tada H, Takeishi A, Harada K, Suzuki M, Tsuda M, Sasanuma H, Takeda S, Sugasawa K, Yasui M, Honma M, Ura K.",Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η,Sci Rep. 2019 Sep 26;9(1):13910. doi: 10.1038/s41598-019-50421-8.,2019
  3. "Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.",Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations,Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.,2019
  4. "Sasanuma H, Sakurai HSM, Furihata Y, Challa K, Palmer L, Gasser SM, Shinohara M, Shinohara A.",Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis,Chromosoma. 2019 Sep;128(3):453-471. doi: 10.1007/s00412-019-00709-5. Epub 2019 Jun 6.,2019
  5. "Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S.",PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching,PLoS One. 2019 Mar 6;14(3):e0213383. doi: 10.1371/journal.pone.0213383. eCollection 2019.,2019
  6. "Zong D, Adam S, Wang Y, Sasanuma H, Callén E, Murga M, Day A, Kruhlak MJ, Wong N, Munro M, Ray Chaudhuri A, Karim B, Xia B, Takeda S, Johnson N, Durocher D, Nussenzweig A.",BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation,Mol Cell. 2019 Mar 21;73(6):1267-1281.e7. doi: 10.1016/j.molcel.2018.12.010. Epub 2019 Jan 28.,2019

2018

  1. "Mohiuddin M, Evans TJ, Rahman MM, Keka IS, Tsuda M, Sasanuma H, Takeda S.",SUMOylation of PCNA by PIAS1 and PIAS4 promotes template switch in the chicken and human B cell lines,Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12793-12798. doi: 10.1073/pnas.1716349115. Epub 2018 Nov 28.,2018
  2. "Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S.",BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes,Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10642-E10651. doi: 10.1073/pnas.1803177115. Epub 2018 Oct 23.,2018
  3. "Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S.",Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms,Environ Mol Mutagen. 2018 Jul;59(6):529-538. doi: 10.1002/em.22201. Epub 2018 May 15.,2018
  4. "Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga SI.",Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma,Int J Radiat Biol. 2018 Jan;94(1):88-96. doi: 10.1080/09553002.2018.1409443. Epub 2017 Dec 12.,2018

2017

  1. "Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH.",Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts,Nucleic Acids Res. 2017 Sep 29;45(17):10079-10088. doi: 10.1093/nar/gkx654.,2017
  2. "Kadoda K, Moriwaki T, Tsuda M, Sasanuma H, Ishiai M, Takata M, Ide H, Masunaga SI, Takeda S, Tano K.","Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells",PLoS One. 2017 Sep 19;12(9):e0185141. doi: 10.1371/journal.pone.0185141. eCollection 2017.,2017
  3. "Al Abo M, Sasanuma H, Liu X, Rajapakse VN, Huang SY, Kiselev E, Takeda S, Plunkett W, Pommier Y.","TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors",Mol Cancer Ther. 2017 Nov;16(11):2543-2551. doi: 10.1158/1535-7163.MCT-17-0110. Epub 2017 Aug 11.,2017
  4. "Tsuda M, Terada K, Ooka M, Kobayashi K, Sasanuma H, Fujisawa R, Tsurimoto T, Yamamoto J, Iwai S, Kadoda K, Akagawa R, Huang SN, Pommier Y, Sale JE, Takeda S, Hirota K.",The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C),Oncotarget. 2017 May 16;8(20):33457-33474. doi: 10.18632/oncotarget.16508.,2017
  5. "Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga SI, Tano K.","Cytotoxicity of Tirapazamine (3-Amino-1,2,4-benzotriazine-1,4-dioxide)-Induced DNA Damage in Chicken DT40 Cells",Chem Res Toxicol. 2017 Feb 20;30(2):699-704. doi: 10.1021/acs.chemrestox.6b00417. Epub 2016 Dec 27.,2017
  6. "Yamada S, Kim S, Tischfield SE, Jasin M, Lange J, Keeney S.",Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice,Cell Cycle,2017,2017/08/19,10.1080/15384101.2017.1361065
  7. "Mimitou EP, Yamada S, Keeney S.",A global view of meiotic double-strand break end resection,Science,2017,2017/01/07,10.1126/science.aak9704

2016

  1. "Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.",Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes,Mol Cell. 2016 Dec 1;64(5):1010. doi: 10.1016/j.molcel.2016.11.028.,2016
  2. "Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.",Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes,Mol Cell. 2016 Nov 3;64(3):580-592. doi: 10.1016/j.molcel.2016.10.011.,2016
  3. "Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J.",Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells,Oncotarget. 2016 Sep 13;7(37):59795-59808. doi: 10.18632/oncotarget.10928.,2016
  4. "Takeda S, Hoa NN, Sasanuma H.",The role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and myths,J Radiat Res. 2016 Aug;57 Suppl 1(Suppl 1):i25-i32. doi: 10.1093/jrr/rrw034. Epub 2016 Jun 15.,2016
  5. "Marchand C, Abdelmalak M, Kankanala J, Huang SY, Kiselev E, Fesen K, Kurahashi K, Sasanuma H, Takeda S, Aihara H, Wang Z, Pommier Y.",Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2,ACS Chem Biol. 2016 Jul 15;11(7):1925-33. doi: 10.1021/acschembio.5b01047. Epub 2016 May 11.,2016
  6. "Mohiuddin, Kobayashi S, Keka IS, Guilbaud G, Sale J, Narita T, Abdel-Aziz HI, Wang X, Ogawa S, Sasanuma H, Chiu R, Oestergaard VH, Lisby M, Takeda S.",The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line,DNA Repair (Amst). 2016 Apr;40:67-76. doi: 10.1016/j.dnarep.2016.02.002. Epub 2016 Mar 2.,2016
  7. "Gothwal SK, Patel NJ, Colletti MM, Sasanuma H, Shinohara M, Hochwagen A, Shinohara A.",The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae,Genetics. 2016 Feb;202(2):497-512. doi: 10.1534/genetics.115.177287. Epub 2015 Dec 1.,2016
  8. "Lange J, Yamada S, Tischfield SE, Pan J, Kim S, Zhu X, Socci ND, Jasin M, Keeney S.","The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair",Cell,2016,2016/10/18,10.1016/j.cell.2016.09.035

2015

  1. "Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A.","Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia",Sci Adv. 2015 Apr 24;1(3):e1400203. doi: 10.1126/sciadv.1400203. eCollection 2015 Apr.,2015
  2. "Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H.","Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines",Genes Cells. 2015 Dec;20(12):1059-76. doi: 10.1111/gtc.12310. Epub 2015 Nov 2.,2015
  3. "Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H.",Smarcal1 promotes double-strand-break repair by nonhomologous end-joining,Nucleic Acids Res. 2015 Jul 27;43(13):6359-72. doi: 10.1093/nar/gkv621. Epub 2015 Jun 18.,2015
  4. "Hoa NN, Kobayashi J, Omura M, Hirakawa M, Yang SH, Komatsu K, Paull TT, Takeda S, Sasanuma H.",BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination,PLoS One. 2015 Apr 24;10(4):e0124495. doi: 10.1371/journal.pone.0124495. eCollection 2015.,2015

2014

  1. "Okamoto S, Narita T, Sasanuma H, Takeda S, Masunaga S, Bessho T, Tano K.",Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines,Genes Cancer. 2014 Jul;5(7-8):285-92. doi: 10.18632/genesandcancer.26.,2014
  2. "Hirota K, Tsuda M, Murai J, Takagi T, Keka IS, Narita T, Fujita M, Sasanuma H, Kobayashi J, Takeda S.",SUMO-targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss,Genes Cells. 2014 Oct;19(10):743-54. doi: 10.1111/gtc.12173. Epub 2014 Sep 10.,2014

2013

  1. "Sasanuma H, Furihata Y, Shinohara M, Shinohara A.",Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase,Genetics. 2013 Aug;194(4):859-72. doi: 10.1534/genetics.113.150615. Epub 2013 Jun 14.,2013
  2. "Sasanuma H, Tawaramoto MS, Lao JP, Hosaka H, Sanda E, Suzuki M, Yamashita E, Hunter N, Shinohara M, Nakagawa A, Shinohara A.",A new protein complex promoting the assembly of Rad51 filaments,Nat Commun. 2013;4:1676. doi: 10.1038/ncomms2678.,2013
  3. "Fujita M, Sasanuma H, Yamamoto KN, Harada H, Kurosawa A, Adachi N, Omura M, Hiraoka M, Takeda S, Hirota K.",Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks,PLoS One. 2013;8(4):e60043. doi: 10.1371/journal.pone.0060043. Epub 2013 Apr 3.,2013

2009

  1. "Kugou K, Fukuda T, Yamada S, Ito M, Sasanuma H, Mori S, Katou Y, Itoh T, Matsumoto K, Shibata T, Shirahige K, Ohta K.",Rec8 guides canonical Spo11 distribution along yeast meiotic chromosomes,Mol Biol Cell. 2009 Jul;20(13):3064-76. doi: 10.1091/mbc.e08-12-1223. Epub 2009 May 13.,2009
  2. "Sasanuma H, Ohta K.",[Formation of DNA double-strand breaks in meiosis],Tanpakushitsu Kakusan Koso. 2009 Mar;54(4 Suppl):459-65.,2009

2008

  1. "Sasanuma H, Hirota K, Fukuda T, Kakusho N, Kugou K, Kawasaki Y, Shibata T, Masai H, Ohta K.",Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination,Genes Dev. 2008 Feb 1;22(3):398-410. doi: 10.1101/gad.1626608.,2008

2007

  1. "Fukuda T, Kugou K, Sasanuma H, Shibata T, Ohta K.",Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination,Nucleic Acids Res. 2008 Feb;36(3):984-97. doi: 10.1093/nar/gkm1082. Epub 2007 Dec 20.,2008
  2. "Kugou K, Sasanuma H, Matsumoto K, Shirahige K, Ohta K.",Mre11 mediates gene regulation in yeast spore development,Genes Genet Syst. 2007 Feb;82(1):21-33. doi: 10.1266/ggs.82.21.,2007
  3. "Sasanuma H, Murakami H, Fukuda T, Shibata T, Nicolas A, Ohta K.","Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114",Nucleic Acids Res. 2007;35(4):1119-33. doi: 10.1093/nar/gkl1162. Epub 2007 Jan 30.,2007

2003

  1. "Araki Y, Kawasaki Y, Sasanuma H, Tye BK, Sugino A.",Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability,Genes Cells. 2003 May;8(5):465-80. doi: 10.1046/j.1365-2443.2003.00648.x.,2003

© IGAKUKEN［Genome Dynamics Project］