研究業績
1) 原著論文
- Bulankina AV, Richter RM, Nettles JH, Yamane D, Grimm C, Karami Y, Stanton RA, Introini B, Hermann J, Charif H, König MS, Stroß C, Ortiz C, Kraus N, Wood D, Galceran F, Abele R, Maigret B, Schinazi RF, Zeuzem S, Biondi RM, Yi M, Tampé R, Kudryashev M, Welsch C. Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling. Sci Adv. . 2026 12(14):eaeb8863.
- Okuwa T, Himeda T, Kobayashi K, Nomura N, Utani K, Koike S, Nakamura A, Higuchi M. Saffold Virus Exploits Integrin αVβ8 and Sulfated Glycosaminoglycans as Cooperative Attachment Receptors for Infection. Nat Commun. 2025 17(1):534.
- Shirasaka Y, Takeuchi F, Koike S, Kato H, Fujita T. A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication. Cell Rep, 2026 45(1):116740.
- Shimizu T, Miyoshi M, Kakinuma S, Tsuchiya J, Yamane D, Watakabe K, Mochida T, Inada K, Yamada K, Shinozaki K, Sato A, Kaneko S, Kawai-Kitahata F, Murakawa M, Nitta S, Nakagawa M, Watanabe M, Asahina Y, Okamoto R.
Bile acid-FXR signaling facilitates the long-term maintenance of hepatic characteristics in human iPSC-derived organoids. Cell Rep, 27;44(5):115675, 2025.
- Shinozaki K, Honda T, Yamaji K, Nishijima E, Ichi I, Yamane D. Impaired ApoB Secretion Triggers Enhanced Secretion of ApoE to Maintain Triglyceride Homeostasis in Hepatoma Cells. J Lipid Res, 100795, 2025
- Matsuda M, Hirai-Yuki A, Kotani O, Kataoka M, Zheng X, Yamane D, Yokoyama M, Ishii K, Muramatsu M, Suzuki R, Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C, PLoS Pathog, 20(3), e1012091, 2024
- Yamaji K, Iwabuchi S, Tokunaga Y, Hashimoto S, Yamane D, Toyama S, Kono R, Kitab B, Tsukiyama-Kohara K, Osawa Y, Hayashi Y, Hishima T, Tateno C, Kimura K, Okanoue T, Kohara M, Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder, Biomed Pharmacother, 166:115379,2023
- Matsumoto M, Modliszewski JL, Shinozaki K, Maezawa R, Perez VM, Ishikawa Y, Suzuki R, McKnight KL, Masaki T, Hirai-Yuki A, Kohara M, Lemon SM, Selitsky SR, Yamane D*, CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling, Nucleic Acids Res, 51(9):4451-4466, 2023 (*Corresponding author)
- Miwatashi W, Ishida M, Takashino A, Kobayashi K, Yamaguchi M, Shitara H, Koike S: Mouse Scarb2 Modulates EV-A71 Pathogenicity in Neonatal Mice. J Virol. 96(15):e0056122. 2022.
doi: 10.1128/jvi.00561-22
- Tamura K, Kohnoe M, Takashino A, Kobayashi K, Koike S, Karwal L, Fukuda S, Vang F, Das SC, Dean HJ: TAK - 021, an inactivated Enterovirus 71 vaccine candidate, provides cross-protection against heterologous sub-genogroups in human scavenger receptor B2 transgenic mice. Vaccine 40(24):3330-3337. 2022.
doi: 10.1016/j.vaccine.2022.04.064
- Yamane D*, Hayashi Y, Matsumoto M, Nakanishi H, Imagawa H, Kohara M, Lemon SM, Ichi I, FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication, Cell Chem Biol. 29(5):799-810.e4, 2022 (*Corresponding author)
- Kobayashi K, Nishimura H, Mizuta K, Nishizawa T, Chu ST, Ichimura H, Koike S: Virulence of enterovirus-A71 fluctuates depending on the phylogenetic clade formed in the epidemic year and epidemic region. J Virol. 95(23):e0151521. 2021.
doi: 10.1128/JVI.01515-21
- Takagi A, Amako Y, Yamane D, Kitab B, Tokunaga Y, El-Gohary A, Kohara M, Tsukiyama-Kohara K, Longer poly(U) stretches in the 3′UTR are essential for replication of the hepatitis C virus genotype 4a clone in in vitro and in vivo, Front Microbiol, 12:764816, 2021
- Honda T, Gomi S, Yamane D, Yasui F, Yamamoto T, Munakata T, Itoh Y, Ogasawara K, Sanada T, Yamaji K, Yasutomi Y, Tsukiyama-Kohara K, Kohara M, Development and Characterization of a Highly Sensitive NanoLuciferase-Based Immunoprecipitation System for the Detection of Anti-Influenza Virus HA Antibodies, mSphere, 6(3):e01342-20, 2021
- Saito M, Itoh Y, Yasui F, Munakata T, Yamane D, Ozawa M, Ito R, Ishigaki H, Nakayama M, Shichinohe S, Yamaji K, Yamamoto N, Ikejiri A, Honda T, Sanada T, Ohuchi M, Masuya K, Sakoda Y, Kida H, Le Thi Quynh Mai, Kawaoka Y, Reid PC, Kubota K, Ogasawara K, Tsukiyama-Kohara K, Suga H, Kohara M, Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models, Nat Commun. 12(1):2654, 2021
- Kobayashi K, Mizuta K, Koike S: Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation. PLoS Pathog. 16(3):e1008428. 2020
doi: 10.1371/journal.ppat.1008428.
- Chu ST, Kobayashi K, Bi X, Ishizaki A, Tran TT, Phung TTB, Pham CTT, Nguyen LV, Ta TA, Khu DTK, Agoh M, Pham AN, Koike S, Ichimura H: Newly emerged enterovirus-A71 C4 sublineage may be more virulent than B5 in the 2015-2016 hand-foot-and-mouth disease outbreak in northern Vietnam. Sci Rep. 10(1):159. 2020.
doi: 10.1038/s41598-019-56703-5.
- Imura A, Sudaka Y, Takashino A, Tamura K, Kobayashi K, Nagata N, Nishimura H, Mizuta K, Koike S: Development of an Enterovirus 71 Vaccine Efficacy Test Using Human Scavenger Receptor B2 Transgenic Mice. J Virol. 94(6) e01921-19, 2020. doi: 10.1128/JVI.01921-19.
- Dultz G, Shimakami T, Schneider M, Murai K, Yamane D, Marion A, Zeitler TM, Stross C, Grimm C, Richter RM, Bäumer K, Yi M, Biondi RM, Zeuzem S, Tampé R, Antes I, Lange CM, Welsch C,Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors. J Biol Chem. 295:13862-13874, 2020
- Hishiki T, Kato F, Nio Y, Watanabe S, Wen Tan NW, Yamane D, Miyazaki Y, Lin CC, Suzuki R, Tajima S, Lim CK, Saijo M, Hijikata M, Vasudevan SG, Takasaki T, Stearoyl-CoA desaturase-1 is required for flavivirus RNA replication, Antiviral Res, 165:42-46 2019
- Sanada T, Tsukiyama-Kohara K, Shin-I T, Yamamoto N, Kayesh MEH, Yamane D, Takano JI, Shiogama Y, Yasutomi Y, Ikeo K, Gojobori T, Mizokami M, Kohara M, Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing, Sci Rep, 9(1):12372, 2019
- Feng H, Sander AL, Moreira-Soto A, Yamane D, Drexler JF, Lemon SM, Hepatovirus 3ABC proteases and evolution of mitochondrial antiviral signaling protein (MAVS), J Hepatol, 71(1):25-34 2019
- Yamane D*, Feng H, Rivera-Serrano EE, Selitsky SR, Hirai-Yuki A, Das A, McKnight KL, Misumi I, Hensley L, Lovell W, González-López O, Suzuki R, Matsuda M, Nakanishi H, Ohto-Nakanishi T, Hishiki T, Wauthier E, Oikawa T, Morita K, Reid LM, Sethupathy P, Kohara M, Whitmire JK, Lemon SM*, Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses, Nat Microbiol, 4(7):1096-1104 2019 (*Corresponding authors)
- Kobayashi K, Sudaka Y, Takashino A, Imura A, Fujii K, Koike S：Amino acid variation at VP1-145 of enterovirus 71 determines attachment receptor usage and neurovirulence in human scavenger receptor B2 transgenic mice. J Virol. 92(15) e00681-18, 2018
- Fujii K, Sudaka Y, Takashino A, Kobayashi K, Kataoka C, Suzuki T, Iwata-Yoshikawa N, Kotani O, Ami Y, Shimizu H, Nagata N, Mizuta K, Matsuzaki Y, Koike S : VP1 amino acid residue 145 of enterovirus 71 is a key residue for its receptor attachment and resistance to neutralizing antibody during cynomolgus monkey infection. J Virol. 92(15) e00682-18, 2018
- Benzine T, Brandt R, Lovell WC, Yamane D, Neddermann P, De Francesco R, Lemon SM, Perelson AS, Ke R, *McGivern DR, NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains, PLoS Pathog, 13(6):e1006343, 2017
- Feng H, Lenarcic EM*, Yamane D*, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, *Lemon SM, NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR, Nat Immunol, 18(12):1299-1309, 2017 (*Equal contributions)
- Yamane D*, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM*, Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants, Nucleic Acids Res, 45(8):4743-4755, 2017 (*Corresponding authors)
- Tokunaga Y, Osawa Y, Ohtsuki T, Hayashi Y, Yamaji K, Yamane D, Hara M, Munekata K, Tsukiyama-Kohara K, Hishima T, Kojima S, *Kimura K, *Kohara M, Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model, Sci Rep, 7(1):325, 2017
- Li Y, Yamane D, Lemon SM, Dissecting the roles of the 5' exoribonucleases Xrn1 and Xrn2 in restricting hepatitis C virus replication, J Virol, 89(9):4857-65, 2015
- Mauger DM, Golden M, Yamane D, Williford S, Lemon SM, Martin DP, Weeks KM, Functionally conserved architecture of hepatitis C virus RNA genomes, Proc Natl Acad Sci USA, 112(12):3692-7, 2015
- Masaki T, Arend KC, Li Y, Yamane D, McGivern DR, Kato T, Wakita T, Moorman NJ, Lemon SM, miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation, Cell Host Microbe, 17(2):217-28, 2015
- Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P, Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C, Sci Rep, 5:7675.2015
- Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR, Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication, Gastroenterology, 148(2):392-402, 2015
- Kotani O, Iwata-Yoshikawa N, Suzuki T, Sato Y, Nakajima N, Koike S, Iwasaki T, Sata T, Yamashita T, Minagawa H, Taguchi F, Hasegawa H, Shimizu H, ＊Nagata N：Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections.
doi: 10.1111/neup.12171 Neuropathology. 35:107-121, 2014
- Yamane D*, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, Oikawa T, Whitmire JK, Heise MT, Dittmer DP, Kao CC, Pitson SM, Merrill AH Jr, Reid LM, Lemon SM*, Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation, Nat Med, 20(8):927-35, 2014 (*Corresponding authors)
- Shimakami T, Honda M, Shirasaki T, Takabatake R, Liu F, Murai K, Shiomoto T, Funaki M, Yamane D, Murakami S, Lemon SM, Kaneko S, The acyclic retinoid Peretinoin inhibits hepatitis C virus replication and infectious virus release in vitro, Sci Rep, 4:4688, 2014
- Yamane D, Dansako H, Lemon SM, Co-immunoprecipitation of Flag-TLR3 or Myc-MSR1 with HCV RNA, Bio Protoc, 4(4):e1061, 2014
- Mohamed YM, Bangphoomi N, Yamane D, Suda Y, Kato K, Horimoto T, Akashi H, Physical interaction between bovine viral diarrhea virus nonstructural protein 4A and adenosine deaminase acting on RNA (ADAR), Arch Virol, 159(7):1735-41, 2014
- Yi M, Hu F, Joyce M, Saxena V, Welsch C, Chavez D, Guerra B, Yamane D, Veselenak R, Pyles R, Walker CM, Tyrrell L, Bourne N, Lanford RE, Lemon SM, Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee, J Virol, 88(7):3678-94, 2014
- Fujii K, Nagata N, SatoY, Ong KC, Wong KT, Yamayoshi S, Shimanuki M, Shitara H, Taya C, Koike S.: Transgenic mouse model for the study of enterovirus 71 neuropathogenesis. Proc Natl Acad Sci USA. 110: 14753-14758, 2013
- Ng CS, Jogi M, Yoo JS, Onomoto K, Koike S, Iwasaki T, Yoneyama M, Kato H, Fujita T.: Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses. J Virol. 87: 9511-9522, 2013
- Yamayoshi S, Ohka S, Fujii K, Koike S.: Functional Comparison of SCARB2 and PSGL1 as Receptors for Enterovirus 71. J Virol. 87:3335-3347, 2013
- Spaniel C, Honda M, Selitsky SR, Yamane D, Shimakami T, Kaneko S, Lanford RE, Lemon SM, microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection, PLoS One. 8(10):e76867, 2013
- Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, Lemon SM, Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring Cells, PLoS Pathog, 9(5):e1003345, 2013
- Kim S, Ishida H, Yamane D, Yi M, Swinney DC, Foung S, Lemon SM, Contrasting Roles of Mitogen-Activated Protein Kinases in Cellular Entry and Replication of Hepatitis C Virus: MKNK1 Facilitates Cell Entry, J Virol, 87(8):4214-24, 2013
- Li Y, Masaki T, Yamane D, McGivern DR, Lemon SM, Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication, Proc Natl Acad Sci USA, 110(5):1881-6, 2013
- Yamayoshi S, Iizuka S, Yamashita T, Minagawa H, Mizuta K, Okamoto M, Nishimura H, Sanjoh S, Katsushima N, Itagaki T, Nagai Y, Fujii K, Koike S: Human SCARB2-dependent Infection by Coxsackievirus A7, A14, A16 and Enterovirus 71. J Virol. 86:5686–5696, 2012
- McWilliam Leitch EC, Cabrerizo M, Cardosa J, Harvala H, Ivanova OE, Koike S, Kroes AC, Lukashev A, Perera D, Roivainen M, Susi P, Trallero G, Evans DJ, Simmonds P: The association of recombination events in the founding and emergence of subgenogroup evolutionary lineages of human enterovirus 71. J Virol. 86:2676-85, 2012
- Abe Y, Fujii K, Nagata N, Takeuchi O, Akira S, Oshiumi H, Matsumoto M, Seya T, Koike S: The Toll-Like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice. J Virol. 86:185-94, 2012
- Shimakami T*, Yamane D*, Welsch C, Hensley L, Jangra RK, Lemon SM, Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus, J Virol, 86:7372-83, 2012 (*, Equally contributed)
- Shimakami T*, Yamane D*, Jangra RK*, Kempf BJ, Spaniel C, Barton DJ, Lemon SM, Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex, Proc Natl Acad Sci USA, 109:941-6, 2012 (*, Equally contributed)
- Oshiumi H, Okamoto M, Fujii K, Kawanishi T, Matsumoto M, Koike S, Seya T: The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection. J Immunol, 187:5320-5327, 2011
- Yamayoshi S & Koike S: Identification of the Human SCARB2 Region That Is Important for Enterovirus 71 Binding and Infection. J Virol. 85:4937-4946, 2011
- Qu L, Feng Z, Yamane D, Liang Y, Lanford RE, Li K, Lemon SM, Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD, PLoS Pathog, 7:e1002169, 2011
- Lanford RE, Feng Z, Chavez D, Guerra B, Brasky KM, Zhou Y, Yamane D, Perelson AS, Walker CM, Lemon SM, Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA, Proc Natl Acad Sci USA, 108:11223-8, 2011
- Shimakami T, Welsch C, Yamane D, McGivern D, Yi M, Zeuzem S, Lemon SM, Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus, Gastroenterology, 140:667-75, 2011
- Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, Babrzadeh F, Gharizadeh B, Grimm D, Kay M, Koike S, Sarnow P, Ronaghi M, Ding SW, Harris E, Chow M, Diamond MS, Kirkegaard K, Glenn JS, Fire AZ.: Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS Pathog. 6(2):e1000764, 2010
- Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, & Koike S: Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses. Virology 390:139-150, 2009
- Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, & Koike S: Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat Med. 15:789-801. 2009
- Ohka S, Igarashi H, Nagata N, Sakai M, Koike S, Nochi T, Kiyono H, & Nomoto A: Establishment of a poliovirus oral infection system in human poliovirus receptor-expressing transgenic mice that are deficient in alpha/beta interferon receptor. J Virol. 81:7902-7912, 2007
- Yoshikawa T, Iwasaki T, Ida-Hosomuma M, Yoneyama M, Fujita T, Horie H, Miyawaza M, Abe S, Simizu B, & Koike S: Role of the alpha/beta interferon response in the acquisition of susceptibility to poliovirus by kidney cells in culture. J Virol. 80: 4313-4325, 2006
- Ida-Hosomua M, Iwasaki T, Yoshikawa T, Nagata N, Sato Y, Sata T, Yoneyama M, Fujita T, Taya C, Yonekawa H, & Koike S: The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus. J Virol. 79: 4460-4469, 2005
- Nagata N, Iwasaki T, Ami Y, Sato Y, Hatano I, Harashima A, Suzaki Y, Yoshii T, Hashikawa T, Sata T, Horiuchi Y, Koike S, Kurata T, & Nomoto A: A poliomyelitis model through mucosal infection in transgenic mice bearing human poliovirus receptor, TgPVR21.Virology. 321: 87-100, 2004
- Ida-Hosonuma M, SasakiY, Toyoda H, Nomoto A, Gotoh O, Yonekawa H, & Koike S: Host range of poliovirus is restricted to simians because of a rapid sequence change of the poliovirus receptor gene during evolution. Arch. Virol. 148: 29-44, 2003
- Ida-Hosonuma M, Iwasaki T, Taya C, Sato Y, Li J, Nagata N, Yonekawa H, & Koike S: Comparison of neuropathogenicity of poliovirus in two transgenic mouse strains expressing human poliovirus receptor with different distribution patterns. J. Gen. Virol. 83:1095-1105, 2002
2) 総説論文
- Zhao JY, Yuan XK, Luo RZ, Wang LX, Gu W, Yamane D*, Feng H*, Phospholipase A and acyltransferase 4/retinoic acid receptor responder 3 at the intersection of tumor suppression and pathogen restriction, Front Immunol, 14:1107239, 2023 (*Corresponding authors)
- Kobayashi K, Koike S: Adaptation and Virulence of Enterovirus-A71. Viruses 13(8):1661 2021.
doi: 10.3390/v13081661
- Feng H, Zhang YB, Gui JF, Lemon SM*, Yamane D*. Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses, PLoS Pathogens, 17(1):e1009220, 2021 (*Corresponding authors)
- Kobayashi K, Koike S: Cellular receptors for enterovirus A71. J Biomed Sci. 27(1):23. 2020. doi: 10.1186/s12929-020-0615-9.
- 小池智：【現代医学・生物学の先駆者たち】細菌学・ウイルス学・免疫学 野本明男(1946-2014) ポリオウイルス病原性研究の開拓者 生体の科学 70巻5号 418-419 (2019)
- 小池智：【ウイルス受容体の発見が臨床にもたらすこと】ポリオウイルス受容体、エンテロウイルス71受容体の臨床ウイルス学への応用 臨床とウイルス 47巻1号 46-52 (2019)
- 小池智：エンテロウイルス71研究の進展 医学のあゆみ 258:1149-1154 (2016)
- Koike S, Nagata N.: A Transgenic Mouse Model of Poliomyelitis. Methods Mol Biol, 2016;1387:129-44. doi: 10.1007/978-1-4939-3292-4_7. PubMed PMID: 26983733
- Yamane D, Lemon SM, Lipid Peroxidation and Hepatitis C Virus Replication, Book Chapter: Hepatitis C Virus. Edited by Miyamura T, Lemon SM, Walker CM, Wakita T. Volume I: Cellular and Molecular Virology, Springer Japan, pp 235-253, 2016
- 小池智：ポリオウイルスの神経指向性のメカニズム Annual Review 2015神経（中外医学社） 121-126 (2015)
- Li Y*, Yamane D*, Masaki T, Lemon SM, The Yin and Yang of Hepatitis C: miR-122 and the Synthesis and Decay of HCV RNA, Nat Rev Microbiol, 13(9):544-58, 2015 (*Equally contributed)
- Koike S：A pH-dependent molecular switch for virion uncoating. Protein Cell, 5(9): 653–654, 2014
- Yamayoshi S, Fujii K, ＊Koike S：Receptors for enterovirus 71. doi: 10.1038/emi.2014.49 Emerg Microbes Infect., 3(7): e53, 2014
- 小池智：ポリオウイルス感染とウイルスセンサー 臨床とウイルス 41：222-228（2013）
- Yamane D, McGivern DR, Masaki T, Lemon SM, Liver injury and disease pathogenesis in chronic hepatitis C, Curr Top Microbiol Immunol, 369:263-88, 2013
- Yamayoshi S, Fujii K, Koike S.: Scavenger receptor B2 as a receptor for hand, foot and mouth disease and severe neurological diseases. Frontiers in Virology. Vol 3. Article 32 (on line publication), 2012
- 島上哲朗，山根大典, Lemon SM, miR-122－Ago2複合体によるC型肝炎ウイルスRNAの安定化, 実験医学 , Vol.30 No.9, 2012
- 小池智：ピコルナウイルスの感染初期過程 ウイルス 第61巻第2号 183-192（2011）
- Koike S, & Nomoto A. Poliomyelitis. In The Picornaviruses, ed. E. Ehrenfeld, E. Domingo, & R.P. Roos. Washington DC, ASM press. 339-351, 2010
- 小池智：ウイルスのトロピズム 化学療法の領域 26: 353-359 （2010）
3) 受賞
- 「ワクチンによる世界ポリオ根絶計画への基盤的貢献」 第41回 「多ヶ谷勇記念ワクチン研究」 イスクラ奨励賞（イスクラ厚生事業団）
Top↑
