研究業績

1)　原著論文

1. Shinozaki K, Honda T, Yamaji K, Nishijima E, Ichi I, Yamane D. Impaired ApoB Secretion Triggers Enhanced Secretion of ApoE to Maintain Triglyceride Homeostasis in Hepatoma Cells. J Lipid Res, 100795, 2025
   

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2. Matsuda M, Hirai-Yuki A, Kotani O, Kataoka M, Zheng X, Yamane D, Yokoyama M, Ishii K, Muramatsu M, Suzuki R, Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C, PLoS Pathog, 20(3), e1012091, 2024
   

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3. Yamaji K, Iwabuchi S, Tokunaga Y, Hashimoto S, Yamane D, Toyama S, Kono R, Kitab B, Tsukiyama-Kohara K, Osawa Y, Hayashi Y, Hishima T, Tateno C, Kimura K, Okanoue T, Kohara M, Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder, Biomed Pharmacother, 166:115379,2023
4. Matsumoto M, Modliszewski JL, Shinozaki K, Maezawa R, Perez VM, Ishikawa Y, Suzuki R, McKnight KL, Masaki T, Hirai-Yuki A, Kohara M, Lemon SM, Selitsky SR, Yamane D*, CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling, Nucleic Acids Res, 51(9):4451-4466, 2023 (*Corresponding author)
   

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   医学研TOPICS

5. Miwatashi W, Ishida M, Takashino A, Kobayashi K, Yamaguchi M, Shitara H, Koike S: Mouse Scarb2 Modulates EV-A71 Pathogenicity in Neonatal Mice. J Virol. 96(15):e0056122. 2022.
   doi: 10.1128/jvi.00561-22
6. Tamura K, Kohnoe M, Takashino A, Kobayashi K, Koike S, Karwal L, Fukuda S, Vang F, Das SC, Dean HJ: TAK - 021, an inactivated Enterovirus 71 vaccine candidate, provides cross-protection against heterologous sub-genogroups in human scavenger receptor B2 transgenic mice. Vaccine 40(24):3330-3337. 2022.
   doi: 10.1016/j.vaccine.2022.04.064
7. Yamane D*, Hayashi Y, Matsumoto M, Nakanishi H, Imagawa H, Kohara M, Lemon SM, Ichi I, FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication, Cell Chem Biol. 29(5):799-810.e4, 2022 (*Corresponding author)
   

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   医学研TOPICS

8. Kobayashi K, Nishimura H, Mizuta K, Nishizawa T, Chu ST, Ichimura H, Koike S: Virulence of enterovirus-A71 fluctuates depending on the phylogenetic clade formed in the epidemic year and epidemic region. J Virol. 95(23):e0151521. 2021.
   doi: 10.1128/JVI.01515-21
9. Takagi A, Amako Y, Yamane D, Kitab B, Tokunaga Y, El-Gohary A, Kohara M, Tsukiyama-Kohara K, Longer poly(U) stretches in the 3′UTR are essential for replication of the hepatitis C virus genotype 4a clone in in vitro and in vivo, Front Microbiol, 12:764816, 2021
10. Honda T, Gomi S, Yamane D, Yasui F, Yamamoto T, Munakata T, Itoh Y, Ogasawara K, Sanada T, Yamaji K, Yasutomi Y, Tsukiyama-Kohara K, Kohara M, Development and Characterization of a Highly Sensitive NanoLuciferase-Based Immunoprecipitation System for the Detection of Anti-Influenza Virus HA Antibodies, mSphere, 6(3):e01342-20, 2021
11. Saito M, Itoh Y, Yasui F, Munakata T, Yamane D, Ozawa M, Ito R, Ishigaki H, Nakayama M, Shichinohe S, Yamaji K, Yamamoto N, Ikejiri A, Honda T, Sanada T, Ohuchi M, Masuya K, Sakoda Y, Kida H, Le Thi Quynh Mai, Kawaoka Y, Reid PC, Kubota K, Ogasawara K, Tsukiyama-Kohara K, Suga H, Kohara M, Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models, Nat Commun. 12(1):2654, 2021
12. Kobayashi K, Mizuta K, Koike S: Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation. PLoS Pathog. 16(3):e1008428. 2020
    doi: 10.1371/journal.ppat.1008428.

    PubMed

13. Chu ST, Kobayashi K, Bi X, Ishizaki A, Tran TT, Phung TTB, Pham CTT, Nguyen LV, Ta TA, Khu DTK, Agoh M, Pham AN, Koike S, Ichimura H: Newly emerged enterovirus-A71 C4 sublineage may be more virulent than B5 in the 2015-2016 hand-foot-and-mouth disease outbreak in northern Vietnam. Sci Rep. 10(1):159. 2020.
    doi: 10.1038/s41598-019-56703-5.

    PubMed

14. Imura A, Sudaka Y, Takashino A, Tamura K, Kobayashi K, Nagata N, Nishimura H, Mizuta K, Koike S: Development of an Enterovirus 71 Vaccine Efficacy Test Using Human Scavenger Receptor B2 Transgenic Mice. J Virol. 94(6) e01921-19, 2020. doi: 10.1128/JVI.01921-19.

    PubMed

15. Dultz G, Shimakami T, Schneider M, Murai K, Yamane D, Marion A, Zeitler TM, Stross C, Grimm C, Richter RM, Bäumer K, Yi M, Biondi RM, Zeuzem S, Tampé R, Antes I, Lange CM, Welsch C,Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors. J Biol Chem. 295:13862-13874, 2020
16. Hishiki T, Kato F, Nio Y, Watanabe S, Wen Tan NW, Yamane D, Miyazaki Y, Lin CC, Suzuki R, Tajima S, Lim CK, Saijo M, Hijikata M, Vasudevan SG, Takasaki T, Stearoyl-CoA desaturase-1 is required for flavivirus RNA replication, Antiviral Res, 165:42-46 2019
17. Sanada T, Tsukiyama-Kohara K, Shin-I T, Yamamoto N, Kayesh MEH, Yamane D, Takano JI, Shiogama Y, Yasutomi Y, Ikeo K, Gojobori T, Mizokami M, Kohara M, Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing, Sci Rep, 9(1):12372, 2019
18. Feng H, Sander AL, Moreira-Soto A, Yamane D, Drexler JF, Lemon SM, Hepatovirus 3ABC proteases and evolution of mitochondrial antiviral signaling protein (MAVS), J Hepatol, 71(1):25-34 2019
19. Yamane D*, Feng H, Rivera-Serrano EE, Selitsky SR, Hirai-Yuki A, Das A, McKnight KL, Misumi I, Hensley L, Lovell W, González-López O, Suzuki R, Matsuda M, Nakanishi H, Ohto-Nakanishi T, Hishiki T, Wauthier E, Oikawa T, Morita K, Reid LM, Sethupathy P, Kohara M, Whitmire JK, Lemon SM*, Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses, Nat Microbiol, 4(7):1096-1104 2019 (*Corresponding authors)
    

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    医学研TOPICS

20. Kobayashi K, Sudaka Y, Takashino A, Imura A, Fujii K, Koike S：Amino acid variation at VP1-145 of enterovirus 71 determines attachment receptor usage and neurovirulence in human scavenger receptor B2 transgenic mice. J. Virol. 92(15) e00681-18, 2018

    PubMed

21. Fujii K, Sudaka Y, Takashino A, Kobayashi K, Kataoka C, Suzuki T, Iwata-Yoshikawa N, Kotani O, Ami Y, Shimizu H, Nagata N, Mizuta K, Matsuzaki Y, Koike S : VP1 amino acid residue 145 of enterovirus 71 is a key residue for its receptor attachment and resistance to neutralizing antibody during cynomolgus monkey infection. J. Virol. 92(15) e00682-18, 2018

    PubMed

22. Benzine T, Brandt R, Lovell WC, Yamane D, Neddermann P, De Francesco R, Lemon SM, Perelson AS, Ke R, *McGivern DR, NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains, PLoS Pathog, 13(6):e1006343, 2017
23. Feng H, Lenarcic EM*, Yamane D*, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, *Lemon SM, NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR, Nat Immunol, 18(12):1299-1309, 2017 (*Equal contributions)
    

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24. Yamane D*, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM*, Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants, Nucleic Acids Res, 45(8):4743-4755, 2017 (*Corresponding authors)
25. Tokunaga Y, Osawa Y, Ohtsuki T, Hayashi Y, Yamaji K, Yamane D, Hara M, Munekata K, Tsukiyama-Kohara K, Hishima T, Kojima S, *Kimura K, *Kohara M, Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model, Sci Rep, 7(1):325, 2017
26. Li Y, Yamane D, Lemon SM, Dissecting the roles of the 5' exoribonucleases Xrn1 and Xrn2 in restricting hepatitis C virus replication, J Virol, 89(9):4857-65, 2015
27. Mauger DM, Golden M, Yamane D, Williford S, Lemon SM, Martin DP, Weeks KM, Functionally conserved architecture of hepatitis C virus RNA genomes, Proc Natl Acad Sci U S A, 112(12):3692-7, 2015
28. Masaki T, Arend KC, Li Y, Yamane D, McGivern DR, Kato T, Wakita T, Moorman NJ, Lemon SM, miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation, Cell Host Microbe, 17(2):217-28, 2015
29. Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P, Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C, Sci Rep, 5:7675.2015
30. Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR, Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication, Gastroenterology, 148(2):392-402, 2015
31. Kotani O, Iwata-Yoshikawa N, Suzuki T, Sato Y, Nakajima N, Koike S, Iwasaki T, Sata T, Yamashita　T, Minagawa H, Taguchi F, Hasegawa H, Shimizu H, ＊Nagata N：Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections.
    doi: 10.1111/neup.12171 Neuropathology.35:107-121, 2014

    PubMed
32. Yamane D*, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, Oikawa T, Whitmire JK, Heise MT, Dittmer DP, Kao CC, Pitson SM, Merrill AH Jr, Reid LM, Lemon SM*, Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation, Nat Med, 20(8):927-35, 2014 (*Corresponding authors)
    

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33. Shimakami T, Honda M, Shirasaki T, Takabatake R, Liu F, Murai K, Shiomoto T, Funaki M, Yamane D, Murakami S, Lemon SM, Kaneko S, The acyclic retinoid Peretinoin inhibits hepatitis C virus replication and infectious virus release in vitro, Sci Rep, 4:4688, 2014
34. Yamane D, Dansako H, Lemon SM, Co-immunoprecipitation of Flag-TLR3 or Myc-MSR1 with HCV RNA, Bio Protoc, 4(4):e1061, 2014
35. Mohamed YM, Bangphoomi N, Yamane D, Suda Y, Kato K, Horimoto T, Akashi H, Physical interaction between bovine viral diarrhea virus nonstructural protein 4A and adenosine deaminase acting on RNA (ADAR), Arch Virol, 159(7):1735-41, 2014
36. Yi M, Hu F, Joyce M, Saxena V, Welsch C, Chavez D, Guerra B, Yamane D, Veselenak R, Pyles R, Walker CM, Tyrrell L, Bourne N, Lanford RE, Lemon SM, Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee, J Virol, 88(7):3678-94, 2014
37. Fujii K, Nagata N, SatoY, Ong KC, Wong KT, Yamayoshi S, Shimanuki M, Shitara H, Taya C, Koike S.: Transgenic mouse model for the study of enterovirus 71 neuropathogenesis. Proc. Natl. Acad. Sci. USA. 110: 14753-14758, 2013

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38. Ng CS, Jogi M, Yoo JS, Onomoto K, Koike S, Iwasaki T, Yoneyama M, Kato H, Fujita T.: Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses. J. Virol. 87: 9511-9522, 2013
39. Yamayoshi S, Ohka S, Fujii K, Koike S.: Functional Comparison of SCARB2 and PSGL1 as Receptors for Enterovirus 71. J. Virol. 87:3335-3347, 2013

    PubMed

40. Spaniel C, Honda M, Selitsky SR, Yamane D, Shimakami T, Kaneko S, Lanford RE, Lemon SM, microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection, PLoS One. 8(10):e76867, 2013
41. Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, Lemon SM, Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring Cells, PLoS Pathog, 9(5):e1003345, 2013
    

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42. Kim S, Ishida H, Yamane D, Yi M, Swinney DC, Foung S, Lemon SM, Contrasting Roles of Mitogen-Activated Protein Kinases in Cellular Entry and Replication of Hepatitis C Virus: MKNK1 Facilitates Cell Entry, J Virol, 87(8):4214-24, 2013
43. Li Y, Masaki T, Yamane D, McGivern DR, Lemon SM, Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication, Proc Natl Acad Sci U S A, 110(5):1881-6, 2013
44. Yamayoshi S, Iizuka S, Yamashita T, Minagawa H, Mizuta K, Okamoto M, Nishimura H, Sanjoh S, Katsushima N, Itagaki T, Nagai Y, Fujii K, Koike S: Human SCARB2-dependent Infection by Coxsackievirus A7, A14, A16 and Enterovirus 71. J Virol. 86:5686–5696, 2012

    PubMed
45. McWilliam Leitch EC, Cabrerizo M, Cardosa J, Harvala H, Ivanova OE, Koike S, Kroes AC, Lukashev A, Perera D, Roivainen M, Susi P, Trallero G, Evans DJ, Simmonds P: The association of recombination events in the founding and emergence of subgenogroup evolutionary lineages of human enterovirus 71. J Virol. 86:2676-85, 2012

    PubMed
46. Abe Y, Fujii K, Nagata N, Takeuchi O, Akira S, Oshiumi H, Matsumoto M, Seya T, Koike S: The Toll-Like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice. J Virol. 86:185-94, 2012

    PubMed
47. Shimakami T*, Yamane D*, Welsch C, Hensley L, Jangra RK, Lemon SM, Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus, J Virol, 86:7372-83, 2012 (*, Equally contributed)
48. Shimakami T*, Yamane D*, Jangra RK*, Kempf BJ, Spaniel C, Barton DJ, Lemon SM, Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex, Proc Natl Acad Sci U S A, 109:941-6, 2012 (*, Equally contributed)
    

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49. Oshiumi H, Okamoto M, Fujii K, Kawanishi T, Matsumoto M, Koike S, Seya T: The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection. J Immunol. 187:5320-5327, 2011

    PubMed
50. Yamayoshi S & Koike S: Identification of the Human SCARB2 Region That Is Important for Enterovirus 71 Binding and Infection. J. Virol. 85:4937-4946, 2011

    PubMed
51. Qu L, Feng Z, Yamane D, Liang Y, Lanford RE, Li K, Lemon SM, Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD, PLoS Pathog, 7:e1002169, 2011
52. Lanford RE, Feng Z, Chavez D, Guerra B, Brasky KM, Zhou Y, Yamane D, Perelson AS, Walker CM, Lemon SM, Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA, Proc Natl Acad Sci U S A, 108:11223-8, 2011
53. Shimakami T, Welsch C, Yamane D, McGivern D, Yi M, Zeuzem S, Lemon SM, Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus, Gastroenterology, 140:667-75, 2011
54. Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, Babrzadeh F, Gharizadeh B, Grimm D, Kay M, Koike S, Sarnow P, Ronaghi M, Ding SW, Harris E, Chow M, Diamond MS, Kirkegaard K, Glenn JS, Fire AZ.: Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS Pathog. 6(2):e1000764, 2010

    PubMed
55. Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, & Koike S: Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses. Virology 390:139-150, 2009

    PubMed
56. Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, & Koike S: Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat. Med. 15:789-801. 2009

    PubMed
57. Ohka S, Igarashi H, Nagata N, Sakai M, Koike S, Nochi T, Kiyono H, & Nomoto A: Establishment of a poliovirus oral infection system in human poliovirus receptor-expressing transgenic mice that are deficient in alpha/beta interferon receptor. J. Virol. 81:7902-7912, 2007

    PubMed
58. Yoshikawa T, Iwasaki T, Ida-Hosomuma M, Yoneyama M, Fujita T, Horie H, Miyawaza M, Abe S, Simizu B, & Koike S: Role of the alpha/beta interferon response in the acquisition of susceptibility to poliovirus by kidney cells in culture. J. Virol. 80: 4313-4325, 2006

    PubMed
59. Ida-Hosomua M, Iwasaki T, Yoshikawa T, Nagata N, Sato Y, Sata T, Yoneyama M, Fujita T, Taya C, Yonekawa H, & Koike S: The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus. J. Virol. 79: 4460-4469, 2005

    PubMed
60. Nagata N, Iwasaki T, Ami Y, Sato Y, Hatano I, Harashima A, Suzaki Y, Yoshii T, Hashikawa T, Sata T, Horiuchi Y, Koike S, Kurata T, & Nomoto A: A poliomyelitis model through mucosal infection in transgenic mice bearing human poliovirus receptor, TgPVR21.Virology. 321: 87-100, 2004

    PubMed
61. Ida-Hosonuma M, SasakiY, Toyoda H, Nomoto A, Gotoh O, Yonekawa H, & Koike S: Host range of poliovirus is restricted to simians because of a rapid sequence change of the poliovirus receptor gene during evolution. Arch. Virol. 148: 29-44, 2003

    PubMed
62. Ida-Hosonuma M, Iwasaki T, Taya C, Sato Y, Li J, Nagata N, Yonekawa H, & Koike S: Comparison of neuropathogenicity of poliovirus in two transgenic mouse strains expressing human poliovirus receptor with different distribution patterns. J. Gen. Virol. 83:1095-1105, 2002

    PubMed

2) 総説論文

1. Zhao JY, Yuan XK, Luo RZ, Wang LX, Gu W, Yamane D*, Feng H*, Phospholipase A and acyltransferase 4/retinoic acid receptor responder 3 at the intersection of tumor suppression and pathogen restriction, Front Immunol, 14:1107239, 2023 (*Corresponding authors)
   

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2. Kobayashi K, Koike S: Adaptation and Virulence of Enterovirus-A71. Viruses 13(8):1661 2021.
   doi: 10.3390/v13081661
3. Feng H, Zhang YB, Gui JF, Lemon SM*, Yamane D*. Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses, PLoS Pathogens, 17(1):e1009220, 2021 (*Corresponding authors)
   

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4. Kobayashi K, Koike S: Cellular receptors for enterovirus A71. J Biomed Sci. 27(1):23. 2020. doi: 10.1186/s12929-020-0615-9.
   

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5. 小池智：【現代医学・生物学の先駆者たち】細菌学・ウイルス学・免疫学　野本明男(1946-2014)　ポリオウイルス病原性研究の開拓者　生体の科学　70巻5号 418-419 (2019)
6. 小池智：【ウイルス受容体の発見が臨床にもたらすこと】ポリオウイルス受容体、エンテロウイルス71受容体の臨床ウイルス学への応用　臨床とウイルス　47巻1号 46-52 (2019)
7. 小池智：エンテロウイルス71研究の進展 医学のあゆみ 258:1149-1154 (2016)
8. Koike S, Nagata N.: A Transgenic Mouse Model of Poliomyelitis. Methods Mol Biol. 2016;1387:129-44. doi: 10.1007/978-1-4939-3292-4_7. PubMed PMID: 26983733
9. Yamane D, Lemon SM, Lipid Peroxidation and Hepatitis C Virus Replication, Book Chapter: Hepatitis C Virus. Edited by Miyamura T, Lemon SM, Walker CM, Wakita T. Volume I: Cellular and Molecular Virology, Springer Japan, pp 235-253, 2016
   

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10. 小池智：ポリオウイルスの神経指向性のメカニズム Annual Review 2015神経（中外医学社）121-126 (2015)
11. Li Y*, Yamane D*, Masaki T, Lemon SM, The Yin and Yang of Hepatitis C: miR-122 and the Synthesis and Decay of HCV RNA, Nat Rev Microbiol, 13(9):544-58, 2015 (*Equally contributed)
    

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12. Koike S：A pH-dependent molecular switch for virion uncoating.　Protein Cell, 5(9): 653–654, 2014
13. Yamayoshi S, Fujii K, ＊Koike S：Receptors for enterovirus 71. doi: 10.1038/emi.2014.49 Emerg. Microbes Infect., 3(7): e53, 2014
    

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14. 小池智：ポリオウイルス感染とウイルスセンサー　臨床とウイルス　41：222-228（2013）
15. Yamane D, McGivern DR, Masaki T, Lemon SM, Liver injury and disease pathogenesis in chronic hepatitis C, Curr Top Microbiol Immunol, 369:263-88, 2013
    

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16. Yamayoshi S, Fujii K, Koike S.: Scavenger receptor B2 as a receptor for hand, foot and mouth disease and severe neurological diseases. Frontiers in Virology. Vol 3. Article 32 (on line publication), 2012
    

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17. 島上哲朗，山根大典, Lemon SM, miR-122－Ago2複合体によるC型肝炎ウイルスRNAの安定化, 実験医学, Vol.30 No.9, 2012
18. 小池智：ピコルナウイルスの感染初期過程　ウイルス　第61巻第2号　183-192（2011）
    

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19. Koike S, & Nomoto A. Poliomyelitis. In The Picornaviruses, ed. E. Ehrenfeld, E. Domingo, & R.P. Roos. Washington DC, ASM press. 339-351, 2010
20. 小池智：ウイルスのトロピズム　化学療法の領域　26: 353-359　（2010）

3) 受賞

1. 「ワクチンによる世界ポリオ根絶計画への基盤的貢献」　第41回 「多ヶ谷勇記念ワクチン研究」 イスクラ奨励賞（イスクラ厚生事業団）