Achievement
研究業績
2014年
論文発表
- Hosokawa M, Arai T, Yamashita M, Tsuji H , Nonaka T, Masuda-Suzukake M , Tamaoka A , Hasegawa M, Akiyama H, (2014) Differential diagnosis of amyotrophic lateral sclerosis from Guillain-Barre syndrome by quantitative determination of TDP-43 in cerebrospinal fluid. Int J Neurosci 124: 344-349
- Asada A, Yamazaki R, Kino Y, Saito T, Kimura T, Miyake M, Hasegawa M, Nukina N, Hisanaga S, (2014) Cyclin-dependent kinase 5 phosphorylates and induces the degradation of ataxin-2. Neurosci Lett 563: 112-117
- Konno T, Tada M, Shiga A, Tsujino A, Eguchi H, Masuda-Suzukake M, Hasegawa M, Nishizawa M, Onodera O, Kakita K, Takahashi H, (2014) Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. Neuropathol Appl Neurobiol 40: 783-788
- Davidson YS, Barker H, Robinson AC, Thompson JC, Harris J, Troakes C, Smith B, Al-Saraj S, Shaw C, Rollinson S, Masuda-Suzukake M, Hasegawa M, Pickering-Brown S, Snowden JS, Mann DMS, (2014) Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. Acta Neuropathol Commun 2: 70.
- Hasegawa M, Watanabe S, Kondo H, Akiyama H, Mann DM, Saito Y, Murayama S, (2014) 3R and 4R tau isoforms in paired helical filaments in Alzheimer's disease. Acta Neuropathol 127: 303-305.
- Yamashita M, Nonaka T, Hirai S, Miwa A, Okado H, Arai T, Hosokawa M, Akiyama H, Hasegawa M. (2014) Distinct pathways leading to TDP-43-induced cellular dysfunctions. Hum Mol Genet 23, 23: 4345-4356.
- Masuda-Suzukake M, Nonaka T, Hosokawa M, Kubo M, Shimozawa A, Akiyama H, Hasegawa M. (2014) Pathological alpha-synuclein propagates through neural networks. Acta Neuropathol Commun. 2:88
- Kawakami I, Hasegawa M, Arai T, Ikeda K, Oshima K, Niizato K, Aoki N, Omi K, Higashi S, Hosokawa M, Hirayasu Y, Akiyama H. (2014) Tau accumulation in the nucleus accumbens in tangle-predominant dementia. Acta Neuropathol Commun. 2:40
- Kametani F (2014) Corticosteroid treatment of Alzheimer's disease: is S100A9/Mrp14 a key target?. Neurobiol Aging 35: e11-e12
- Kametani F. (2014) S100A9/Mrp14 Plays an Important Role in Ab Amyloidosis Enhancement. J Neurol Stroke 1: 00006
- Nakamura A, Okigaki M, Miura N, Suzuki C, Ohno N, Kametani F, Hamaoka K. (2014) Involvement of mannose-binding lectin in the pathogenesis of Kawasaki disease-like murine vasculitis. Clin Immunol 153: 64-72
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学会発表等
招待講演
- Hasegawa M.Prion-like properties of pathological proteins from diseased
brains. Brain Conference 2014, Symposium 4 「Pathological propagation in
neurodegenerative diseases」Seoul, Korea. [2014. 11. 6.]
- Hasegawa M.Prion-like features in alpha-synucleinopathies. XVIIIth International Congress of Neuropathology 2014. W3: Prion-like mechanisms in neurodegenerative disorders. Rio de Janeiro, Brazil . [2014. 9. 15.]
- Hasegawa M.Pathological alpha-synuclein spreading explain the disease progression. Neuroscience 2014. Joint Symposium of the Japan Neuroscience Society and the Korean Society of Brain and Neuroscience: Molecular Mechanisms underlying Parkinson Disease. Yokohama, Japan . [2014. 9. 12.]
- Nonaka T. Prion-like properties of pathological TDP-43 aggregates from diseased brains. Neuroscience 2014・Symposium, Yokohama . [2014. 9. 11]
- Hasegawa M.Prion-like mechanism in propagation of Lewy body disease. 55th Annual Meeting of the Japanese Society of Neurology, Symposium: Propagation and Transmission of Misfolded Proteins and Pathologies in Prion Disease and Other Protein-Misfolding Disorders, Hakata . [2014. 5. 24]
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