研究業績 2024年度（2024年4月～2025年3月）
原 著2024
スタッフ * 責任著者
- *Ide S, Iwase N, Arai K, Kojima M, Ushiyama S, Ikeda K (2025).
Inhibitory effects of the selective mu-opioid receptor antagonist UD-030 on methamphetamine-induced conditioned place preference. (Open Access)
Neuropsychopharmacol Rep 45(1):e12503. 査読有 doi: 10.1002/npr2.12503. - *Ohi K, Nishizawa D, Saito T, Goto T, Kubota I, Shinoda T, Fujikane D, Hasegawa J, Sato N, Tanioka F, Sugimura H, Ikeda K, Shioiri T (2024) .
Dietary habits and genetic susceptibility: Correlations between nutritional intake and genetic risks for schizophrenia and bipolar disorder. (Open Access)
Transl Psychiatry 14(1):404. 査読有 doi: 10.1038/s41398-024-03105-5 - Kosaki Y, Nishizawa D, Hasegawa J, Yoshida K, *Ikeda K, Ichinohe T (2024) .
Gamma-aminobutyric acid type A receptor beta1 subunit gene polymorphisms are associated with the sedative and amnesic effects of midazolam. (Open Access)
Mol Brain 17(1):70. 査読有 doi: 10.1186/s13041-024-01141-2. - Zou R, Nishizawa D, Inoue R, Hasegawa J, Ebata Y, Nakayama K, Hara A, Sumikura H, Kitade M, *Hayashida M, Ikeda K, *Kawagoe I (2024) .
Effect of A118G (rs1799971) single-nucleotide polymorphism of the mu-opioid receptor OPRM1 gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery. (Open Access)
Neuropsychopharmacol Rep 44(3):650-357. 査読有 doi: 10.1002/npr2.12468. - Kang Y, Nishizawa D, Ohka S, Terui T, Ishitani K, Morino R, Yokota M, Hasegawa J, Ebata Y, Nakayama K, Koshika K, Ichinohe T, *Ikeda K (2024) .
TMEM132C rs7296262 single-nucleotide polymorphism is significantly associated with nausea induced by opioids administered for cancer pain and postoperative pain. (Open Access)
Int J Mol Sci 25(16):8845. 査読有 doi: 10.3390/ijms25168845. -
Ogawa T, Yamada S, Fukushi S, Imai Y, Kawada J, Ikeda K, Ohka S, *Kaneda S (2024)
Formation and long-term culture of hiPSC-derived sensory nerve organoids using microfluidic devices. (Open Access)
Bioengineering 11(8):794. 査読有 doi: 10.3390/bioengineering11080794. - Araida J, Ohka S, Soeda M, Nishizawa D, Hasegawa J, Nakayama K, Ebata Y, Ogai Y, *Fukuda K, Ikeda K (2024) .
rs12411980 single-nucleotide polymorphism related to PRTFDC1 expression is significantly associated with phantom tooth pain. (Open Access)
Mol Pain 2:17448069241272215. 査読有 doi: 10.1177/17448069241272215. - Okitsu M, Fujita M, Moriya Y, Kotajima-Murakami H, Ide S, Kojima R, Sekiyama K, Takahashi K, *Ikeda K (2024) .
Mouse model of Parkinson’s disease with bilateral dorsal striatum lesion with 6-hydroxydopamine exhibits cognitive apathy-like behavior. (Open Access)
Int J Mol Sci 25(14):7993. 査読有 doi: 10.3390/ijms25147993. - Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T, Darwish M, Nishizono H, Takao K, Sapkota K, Nakazawa K, Takagi T, Fujisawa H, Sugimura Y, Yamanishi K, Rajagopal L, Hannah LD, Meltzer HY, Yamamoto T, Wakatsuki S, Araki T, Tabuchi K, Numakawa T, Kunugi H, Huang FL, Hayata-Takano A, Hashimoto H, Tamada K, Takumi T, Kasahara T, Kato T, Graef IA, Crabtree GR, Asaoka N, Hatakama H, Kaneko S, Kohno T, Hattori M, Hoshiba Y, Miyake R, Obi-Nagata K, Hayashi-Takagi A, Becker LJ, Yalcin I, Hagino Y, Kotajima-Murakami H, Moriya Y, Ikeda K, Kim H, Kaang BK, Otabi H, Yoshida Y, Toyoda A, Komiyama NH, Grant SGN, Ida-Eto M, Narita M, Matsumoto K, Okuda-Ashitaka E, Ohmori I, Shimada T, Yamagata K, Ageta H, Tsuchida K, Inokuchi K, Sassa T, Kihara A, Fukasawa M, Usuda N, Katano T, Tanaka T, Yoshihara Y, Igarashi M, Hayashi T, Ishikawa K, Yamamoto S, Nishimura N, Nakada K, Hirotsune S, Egawa K, Higashisaka K, Tsutsumi Y, Nishihara S, Sugo N, Yagi T, Ueno N, Yamamoto T, Kubo Y, Ohashi R, Shiina N, Shimizu K, Higo-Yamamoto S, Oishi K, Mori H, Furuse T, Tamura M, Shirakawa H, Sato DX, Inoue YU, Inoue T, Komine Y, Yamamori T, Sakimura K, *Miyakawa T (2024) .
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. (Open Access)
eLife 12:RP89376. 査読有 doi: 10.7554/eLife.89376.2.
総 説2024
スタッフ * 責任著者
- *Ide S, Ikeda K (2024) .
Caenorhabditis elegans for opioid addiction research.
Curr Opin Neurobiol 88:102914. 査読有 doi: 10.1016/j.conb.2024.102914. - 井手聡一郎, 森屋由紀, 池田和隆 (2024)
規制薬物使用研究支援.
生体の科学 75(5):458-459. 査読無 - 大岡静衣, 西澤大輔, 池田和隆 (2024)
疼痛・鎮痛の薬理学.
眼薬理 38(1):7-10. 査読無 - Nishizawa D, *Ikeda K (2024)
Chapter 4: Pharmacology and mechanisms of addiction.
In: Addiction Medicine (Third Edition)【分担執筆】pp72-74. UK: OXFORD UNIVERSITY PRESS. 査読無
学会等発表（招待講演）2024
スタッフ * 学会発表者
- *池田和隆 (2024)
疼痛・鎮痛個人差の遺伝子メカニズム.
第29回一般社団法人日本口腔顔面痛学会学術大会, 東京 [2024/12/01]. - *西澤大輔, 池田和隆 (2024)
鎮痛薬・疼痛感受性個人差に寄与する遺伝要因の解明とその臨床応用.
第46回日本疼痛学会, 東京 [2024/11/16]. - *Ikeda K (2024)
Models of schizophrenia: A focus on neurotransmitter systems.
Master Class in Behavioral Medicine, Metro Manila, Philippines [2024/09/26]. - *Ikeda K (2024)
Advances in addiction research and treatment.
334th Dr. Luis Maria Alvarez Guerrero Memorial Lecture, Manila, Philippines [2024/09/25]. - *Ikeda K (2024)
Collaborations and developments in addiction research.
2024 Summer Symposium of the Taiwanese Society of Addiction Science and the Joint Academic Conference of the National Health Research Institutes and China Medical University, Taipei, Taiwan [2024/07/27].
学会等発表（その他）2024
スタッフ * 学会発表者
- *大井一高, 西澤大輔, 藤兼大輔, 長谷川準子, 佐藤直美, 谷岡書彦, 椙村春彦, 池田和隆, 塩入俊樹 (2025)
Correlations between dietary nutritional intake and genetic risks for schizophrenia and bipolar disorder.
2024年度 文部科学省 学術変革領域研究 学術研究支援基盤形成 先端モデル動物支援プラットフォーム 成果発表会, 大津 [2025/02/13]. - *Nishizawa D, Mieda T, Tsujita M, Nakagawa H, Yamaguchi S, Kasai S, Hasegawa J, Ebata Y, Nakayama K, Kitamura A, Hayashida M, Ikeda K (2024)
Genome-wide association study identifies candidate genetic variants associated with postoperative opioid-related side effects (nausea/vomiting and sedation) in patients undergoing laparoscopic-assisted colectomy (LAC).
The American Society of Human Genetics 74th Annual Meeting, Denver, USA [2024/11/06]. - *Nishizawa D, Mieda T, Tsujita M, Nakagawa H, Yamaguchi S, Kasai S, Hasegawa J, Ebata Y, Nakayama K, Kitamura A, Hayashida M, Ikeda K (2024)
Genome-wide association study identifies candidate loci associated with postoperative nausea/vomiting and sedation.
日本人類遺伝学会第69回大会, 札幌 [2024/10/12]. - *Ichinose H, Aida R, Nago-Iwashita Y, Moriya Y, Ide S, Ikeda K (2024)
Control of the methamphetamine-responses by modulating the activity of tyrosine hydroxylase.
NEURO2024, 福岡 [2024/07/24-27]. - *井手聡一郎, 藤田雅代, 池田和隆 (2024)
ドパミン関連遺伝子改変マウスを用いたニコチン依存と行動嗜癖の解析.
公益財団法人喫煙科学研究財団 第38回令和5年度助成研究発表会, 東京 [2024/07/19]. - *西澤大輔, 長谷川準子, 池田和隆 (2024)
ニコチン等物質依存脆弱性・重症度個人差におけるアルコール代謝関連遺伝子多型の関与.
公益財団法人喫煙科学研究財団 第38回令和5年度助成研究発表会, 東京 [2024/07/19]. - *Nishizawa D, Morino R, Inoue R, Ohka S, Kasai S, Hasegawa J, Ebata Y, Nakayama K, Sumikura H, Hayashida M, Yokota M, Ikeda K (2024)
Genome-wide association study identifies candidate genetic polymorphisms associated with postoperative nausea and/or vomiting.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/26]. - *Kasai S, Nishizawa D, Higuchi S, Ikeda K (2024)
Association between Proopiomelanocortin gene variation and alcohol dependence in Japanese.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/26]. - *Ohka S, Kawaji H, Yamada S, Fukui Y, Hasegawa J, Nishizawa D, Fukushi S, Ebihara H, Ikeda K (2024)
Truncated HS3ST4 expressed downstream of chronic painassociated single nucleotide polymorphisms regulates transcriptional promoter activity.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/26]. - *Ichinose H, Aida R, Nago-Iwashita Y, Moriya Y, Ide S, Ikeda K (2024)
Modulation of the dopaminergic neurotransmission by controlling the activity of tyrosine hydroxylase.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/26]. - *西澤大輔, 池田和隆 (2024)
鎮痛薬・疼痛感受性個人差の遺伝要因の解明と臨床応用.
第17回日本緩和医療薬学会年会, 東京 [2024/05/25]. - *井手聡一郎, 池田和隆 (2024)
ドパミン関連遺伝子改変マウスを用いたアディクション解析.
第54回日本神経精神薬理学会 第34回日本臨床精神神経薬理学会 合同年会, 東京 [2024/05/25]. - *Fujita M, Ide S, Okitsu M, Ikeda K (2024)
Analysis of dopamine transporter-expressing neuron-specific tyrosine hydroxylase knockout mice.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/25]. - *Okitsu M, Fujita M, Takahashi K, Ikeda K (2024)
Transversal investigation of apathic behaviors in a Parkinson’ s disease mouse model with 6-hydroxydopamine lesioning in the bilateral dorsal striatum.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/25]. - *Kotajima H, Sato A, Kasai S, Hagino Y, Tanaka M, Takamatsu Y, Nishito Y, Uchino S, Ikeda K (2024)
Effects of behavioral therapy on mouse model of ASD associated with tuberous sclerosis complex and DNA methylation analysis.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/25]. - *Kang Y, Ohka S, Nishizawa D, Hasegawa J, Nakayama K, Ebata Y, Terui T, Ishitani K, Morino R, Yokota M, Koshika K, Ichinohe T, Ikeda K (2024)
TMEM132C rs7296262 single nucleotide polymorphism showed significant associations with nausea induced by opioids administered for cancer pain or post-operative pain.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/25]. - *Ikeda K, Ide S (2024)
G-protein-activated inwardly rectifying potassium (GIRK) channels: A potential therapeutic frontier for addiction.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/25]. - *Ohi K, Shimada M, Soda M, Nishizawa D, Fujikane D, Takai K, Kuramitsu A, Muto Y, Sugiyama S, Hasegawa J, Kitaichi K, Ikeda K, Shioiri T (2024)
Genome-wide DNA methylation risk scores for schizophrenia derived from blood and brain tissues further explain the genetic risk in patients stratified by polygenic risk scores for schizophrenia and bipolar disorder.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/24]. - *Nakamoto Y, Kaga M, Kawana S, Nakamura K, Ikeda K, Yoshii M (2024)
Gender differences in the stress response of patients with atopic dermatitis, alopecia areata, and premenstrual dysphoric disorder as observed by translocator protein 18 kDa (TSPO).
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/24]. - *Yamaguchi Y, Kasai S, Hasegawa J, Ikeda K (2024)
Alcohol intake is associated with eating habits during development.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/24]. - *Moriya Y, Kasahara Y, Shimada M, Sakakibara Y, Fujii H, Nagase H, Ide S, Ikeda K, Hall FS, Uhl GR, Sora I (2024)
Sex differences in the reduction of hopelessness in mu opioid receptor deficient mice by additive effects of delta opioid receptor agonists.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/24]. - *Ide S, Ikekubo Y, Mishina M, Hashimoto K, Ikeda K (2024)
The role of NMDA receptor GluN2D subunit in GABA neurons on the long-lasting antidepressant effects of ketamine enantiomers and their metabolites.
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京 [2024/05/24].
その他の発表2024
スタッフ
- *池田和隆 (2024)
がん関連疼痛の個別化医療 [講演]
順天堂大学大学院特別講義, オンライン開催 [2024/06/26].
特記事項2024
スタッフ
- 池田和隆 (2025)
生理機能解析成果 ワークショップ [座長]
2024年度文部科学省学術変革領域研究 学術研究支援基盤形成 先端モデル動物支援プラットフォーム 成果発表会, 琵琶湖ホテル, 大津 [2025/02/13]. - 池田和隆 (2024)
シンポジウム1 (S1)：ゲノム／エピゲノム疼痛解析とプレシジョンメディシン [座長]
第46回日本疼痛学会, TOC有明コンベンションホール, 東京 [2024/11/16]. - 池田和隆 (2024)
シンポジウム1「研究成果の国際発信：アソシエートジャーナルNeuropsychopharmacology Reports誌の活用法」 [座長]
2024年度 アルコール・薬物依存関連学会 合同学術総会, 砂防会館 シェーンバッハ・サボー, 東京 [2024/09/19]. - 池田和隆 (2024)
シンポジウム1「研究成果の国際発信：アソシエートジャーナルNeuropsychopharmacology Reports誌の活用法」 [オーガナイザー]
2024年度 アルコール・薬物依存関連学会 合同学術総会, 砂防会館 シェーンバッハ・サボー, 東京 [2024/09/19]. - 井手聡一郎 (2024)
市民公開講座 [座長]
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京国際フォーラム, 東京 [2024/05/26]. - 池田和隆 (2024)
Plenary 5 [座長]
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京国際フォーラム, 東京 [2024/05/25]. - 池田和隆 (2024)
Symposium 16 [座長]
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京国際フォーラム, 東京 [2024/05/25]. - 古田島浩子 (2024)
Short Communications 18 [座長]
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京国際フォーラム, 東京 [2024/05/25]. - 森屋由紀 (2024)
Featured Communications 1 [座長]
The 35th CINP World Congress of Neuropsychopharmacology (CINP2024), 東京国際フォーラム, 東京 [2024/05/24].