Achievements

2016年

1. Yasui F., Itoh Y., Ikejiri A., Kitabatake M., Sakaguchi N., Munekata K., Shichinohe S., Hayashi Y., Ishigaki H., Nakayama M., Sakoda Y., Kida H., Ogasawara K., Kohara M. : Sensitization with vaccinia virus encoding H5N1 hemagglutinin restores immune potential against H5N1 influenza virus. Scientific Reports 2016 Nov 28;6:37915.
2. Sanada T., Hirata Y., Naito Y., Yamamoto N., Kikkawa Y., Ishida Y., Yamasaki C., Tateno C., Ochiya T., Kohara M. :　Transmission of HBV-DNA mediated by ceramide-triggered extracellular vesicles. Cellular and Molecular Gastroenterology and Hepatology 2016 Oct 24;3(2):272-283.
3. Kouwaki T., Fukushima Y., Daito T., Yamamoto N., Mifsud e. J., Leong C. R., Tsukiyama-Kohara K., Kohara M., Matsumoto M., Seya T., Oshiumi H., : Exosome RNA released by hepatocytes regulates innate immune responses to hepatitis B virus infection. Frontiers in immunology 2016 Aug 31;7:335.
4. Saga R., Fujimoto A., Watanabe N., Matsuda M., Hasegawa M., Watashi K., Aizaki H., Nakamura N., Tajima S., Takasaki T., Konishi E., Kato T., Kohara M., Takeyama H., Wakita T., Suzuki R., : Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus. Sci rep. Scientific Reports 2016 Jun 27;6:28688.
5. Sugata K., Yasunaga J., Miura M., Akari H., Utsunomiya A., Nosaka K., Watanabe Y., Suzushima H., Koh KR., Nakagawa M., Kohara M., Matsuoka M. : Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodel effects of anti-CCR4 antibody. Scientific Reports. 2016 Jun 2;6:27150.
6. Kubota N., Nomoto M., Hwang GW., Watanabe T., Kohara M., Wakita T., Naganuma A., Kuge S. Hepatitis C virus inhibitor synergism suggests multistep interactions between heat-shock protein 90 and hepatitis C virus replication. World J. Hepatol. 18;8(5):282-90 2016

2015年

1. Makoto Saito, Takashi Takano, Tomohiro Nishimura, MichinoriKohara, Kyoko Tsukiyama-Kohara.3β-Hydroxysterol Δ24-reductase on the Surface of Hepatitis C Virus-related Hepatocellular Carcinoma Cells can be a Target for Molecular Targeting Therapy.PLoS ONE(2015) in press.
2. Yutaka Amako, Tsubasa Munakata, Michinori Kohara, Aleem Siddiqui, Chris Peers and, Mark Harris. Hepatitis C virus attenuates mitochondrial lipid β-oxidation by down-regulating mitochondrial trifunctional protein expression.Journal of Virology(2015) in press.
3. Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A. The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus.Immunity. 2015 Jan 20;42(1):123-32. doi: 10.1016/j.immuni.2014.12.016. Epub 2014 Dec 18.
4. Sayeh Ezzikouri, Tomohiro Nishimura, Michinori Kohara, Soumaya Benjelloun, Yoichiro Kino, Kazuaki Inoue, Akira Matsumori, Kyoko Tsukiyama-Kohara. Inhibitory Effects of Pycnogenol® on Hepatitis C Virus Replication.Antiviral Research.2015 Jan;113:93-102. doi: 10.1016/j.antiviral.2014.10.017. Epub 2014 Nov 20.