演者と演題 Speakers and Presentation title |
- 10:00~10:20
Opening Remarks Masato Hasegawa (Tokyo Metropolitan Institute of Medical Science, Japan)
- Session 1: Pathology and Propagation (Chair, Makoto Higuchi)
- 10:20~11:10
Virginia Man-Yee Lee (University of Pennsylvania School of Medicine, USA) - “Transmission of Misfolded Proteins in Neurodegenerative Disorders: A Common Mechanism of Disease Progression”
- 11:10~11:30
Norihito Uemura (Kyoto University School of Medicine, Japan) - “Pathological activity of α-synuclein strains in mice and monkeys”
- 11:30~11:50
Maiko Uemura (Osaka Metropolitan University Graduate School of Medicine, Japan) - “Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease”
<Lunch> 11:50~13:20
- Session 2: Amyloids and Structures(Chair, Masato Hasegawa)
- 13:20~14:10
Michel Goedert (MRC Laboratory of Molecular Biology, UK) - “Cryo-EM Structures of Amyloid Filaments from Human Brains”
- 14:10~14:30
Airi Tarutani (Tokyo Metropolitan Institute of Medical Science, Japan) - “Distinct tau filament folds drive prion-like templated amplification”
- 14:30~14:50
Shotaro Shimonaka (Tokyo Metropolitan Institute of Medical Science / Juntendo University School of Medicine, Japan) - “Tau strain-typing and anti-aggregation effect of artificial Tau mutant”
<Coffee break> 14:50~15:20
- Session 3: Diagnosis and Therapy (Chair, Ryosuke Takahashi)
- 15:20~16:10
Makoto Higuchi (National Institutes for Quantum Science and Technology / Osaka Metropolitan University Graduate School of Medicine, Japan) - “Neuroimaging of dementias and movement disorders targeting protein fibril folds”
- 16:10~17:00
Catherine Mummery (University College London, UK) - “Tau-targeting antisense oligonucleotide MAPTRx in Alzheimer's disease”
- 17:00~17:10
Closing Remarks - Ryosuke Takahashi (Kyoto University School of Medicine, Japan)
- 17:15
Banquet
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