- この都医学研セミナーは終了しました。-
演者 | Heiko Luhmann University Medical Center Mainz, Professor |
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会場 | オンライン(Zoom) |
日時 | 2022年6月27日(月曜日)15:30~16:30 |
世話人 | 丸山 千秋 脳神経回路形成プロジェクトリーダー |
参加自由 | 詳細は下記問合せ先まで |
お問い合わせ |
研究推進課 普及広報係 電話 03-5316-3109 |
During early development, distinct neuronal cell types and neuronal circuits are transiently expressed in the cerebral cortex. Cajal-Retzius neurons (CRNs) in the marginal zone (later cortical layer 1) and subplate neurons (SPNs) in lower cortical layer play important roles in forming the cortical architecture (layers and columns) and in guiding synaptic connectivity. Both cell types largely disappear during early development; in rodents mostly during the first postnatal week.
This talk will give an overview (1) on the unique functions of CRNs and SPNs in newborn rodent cortex, (2) how early neuronal network activity controls the maturation of the cortex, and (3) how synchronized activity patterns control the programmed cell death (apoptosis) of transient neurons.