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演者 | Robert Barry Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Assistant Professor |
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会場 | 対面式(講堂) |
日時 | 2023年10月3日(火曜日)11:00~12:00 |
世話人 | 西村 幸男 脳機能再建プロジェクトリーダー |
参加自由 | 詳細は下記問合せ先まで |
お問い合わせ |
研究推進課 普及広報係 電話 03-5316-3109 |
Magnetic resonance imaging of the brain and spinal cord at 7 Tesla offers new opportunities to visualize structures with high spatial resolution and enhanced conspicuity, and to detect functional networks with greater sensitivity. This talk will highlight some of the technical challenges and recent advancements in structural and functional spinal cord imaging at 7 Tesla. For example, sub-millimeter in-plane fMRI acquisitions are desirable and achievable, but published studies in the spinal cord have had modest temporal resolution (>2 sec). Using a custom-built 7T pTx spine coil, we demonstrate sub-second and sub-millimeter cervical cord fMRI for the first time. Employing a 3D multi-shot sequence with appropriate phase corrections and NORDIC denoising, our data demonstrate temporal signal-to-noise ratios comparable to those of supra-second protocols, and we replicate bilateral functional connectivity patterns previously published in the cord. Realizing sub-second and sub-millimeter spinal cord fMRI opens new avenues of discovery that echo what has been reported through high spatiotemporal resolution brain fMRI, and the spinal cord remains one of the areas in which higher fields and resolution should have high impact.