- この都医学研セミナーは終了しました。-
| 演者 | Zoltán Molná Professor/Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK |
|---|---|
| 会場 | ハイブリッド（講堂＋Zoom） |
| 日時 | 2025年4月9日（水曜日）10:00～12:00 |
| 世話人 | 丸山 千秋 脳神経回路形成プロジェクト |
| 参加自由 | 詳細は下記問合せ先まで |
| お問い合わせ |
研究推進課 普及広報係 電話 03-5316-3109 |
To understand how the neocortex emerged during mammalian evolution we need to understand the evolution of the development of the pallium, the source of the neocortex. Accumulation of subtle modifications from very early brain development accounted for the diversification of vertebrate pallia and the origin of the neocortex. These cells and germinative compartments generate diverse neuronal populations that migrate and mix with each other through radial and tangential migrations in a taxon-specific fashion. Together, these early variations had a profound influence on neurogenetic gradients, lamination, positioning, and connectivity. The origin of cells and their developmental trajectory are fundamental to understand evolutionary changes. I shall compare the development of the homologous pallial sectors in sauropsids and mammals, with a particular focus on cell lineage, in search of the key changes that led to the appearance of the mammalian neocortex.
